Serum Vitamin D and Gingival Crevicular Fluid Levels of Osteocalcin and N-Terminal Telopeptide
NCT ID: NCT06871631
Last Updated: 2025-03-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
120 participants
OBSERVATIONAL
2018-06-10
2025-02-15
Brief Summary
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Detailed Description
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A total of 120 male participants aged 25-40 years were enrolled, comprising 60 periodontally healthy individuals and 60 patients diagnosed with periodontitis. Participants were further categorized into subgroups based on their serum vitamin D levels (0-10 ng/ml, 11-20 ng/ml, and 21-30 ng/ml). GCF samples were collected from maxillary premolar and molar sites and analyzed using enzyme-linked immunosorbent assay (ELISA) to measure osteocalcin and NTx concentrations.
Conditions
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Study Design
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OTHER
CROSS_SECTIONAL
Study Groups
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Patients with periodontitis and 25(OH)D levels of 0-10 ng/ml
Patients diagnosed with periodontitis who have serum 25-hydroxyvitamin D \[25(OH)D\] levels ranging from 0 to 10 ng/ml.
No interventions assigned to this group
Patients with periodontitis and 25(OH)D levels of 11-20 ng/ml
Patients diagnosed with periodontitis who have serum 25-hydroxyvitamin D \[25(OH)D\] levels ranging from 11 to 20 ng/ml.
No interventions assigned to this group
Patients with periodontitis and 25(OH)D levels of 21-30 ng/ml
Patients diagnosed with periodontitis who have serum 25-hydroxyvitamin D \[25(OH)D\] levels ranging from 21 to 30 ng/ml.
No interventions assigned to this group
Periodontally healthy patients and 25(OH)D levels of 0-10 ng/ml
Periodontally healthy patients with serum 25-hydroxyvitamin D \[25(OH)D\] levels between 0 and 10 ng/ml.
No interventions assigned to this group
Periodontally healthy patients and 25(OH)D levels of 11-20 ng/ml
Periodontally healthy patients with serum 25-hydroxyvitamin D \[25(OH)D\] levels between 11 and 20 ng/ml.
No interventions assigned to this group
Periodontally healthy patients and 25(OH)D levels of 21-30 ng/ml
Periodontally healthy patients with serum 25-hydroxyvitamin D \[25(OH)D\] levels between 21 and 30 ng/ml.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Smokers
* Individuals with systemic diseases (Diabetes Mellitus, Hyperthyroidism, -Malabsorption, Liver and Renal Failure, or those receiving osteoporosis treatment)
* Individuals who have undergone periodontal treatment within the last 6 months
* Individuals on regular medication
* Individuals who did not provide informed consent
* Individuals with poor cooperation
25 Years
40 Years
MALE
Yes
Sponsors
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Ondokuz Mayıs University
OTHER
Responsible Party
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Atanur Sarioglu
Research assistant
Principal Investigators
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Atanur Sarioglu, DDS
Role: PRINCIPAL_INVESTIGATOR
Ondokuz Mayıs University, Department of Periodontology
Locations
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Department of Periodontology, Faculty of Dentistry, Ondokuz Mayis University
Samsun, Atakum, Turkey (Türkiye)
Countries
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Other Identifiers
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OMU KAEK protokol no: 2017/60
Identifier Type: -
Identifier Source: org_study_id
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