Analgesia Following Lumbar Discectomy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

130 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-12

Study Completion Date

2026-03-31

Brief Summary

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Lumbar discectomy surgeries are often the last option for patients with disc herniation who do not improve with conservative treatments. However, these procedures can lead to significant perioperative pain that may become chronic without effective management. While intravenous opioids are commonly used for pain control, they can complicate recovery and pose risks like dependence. In contrast, regional anesthetic techniques offer advantages such as quicker recovery, better postoperative pain relief, and reduced opioid use, which can lead to shorter hospital stays. Our study aims to compare the effectiveness of the retrolaminar block with local wound infiltration for pain management following posterior lumbar discectomy surgeries, potentially improving patient outcomes.

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Detailed Description

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Lumbar discectomy surgeries are the last resort for disc herniation patients not responding to conservative treatment. However, these surgeries are associated with annoying perioperative pain that could be severe and progress to chronic pain if not managed properly. There is no consensus regarding the best approach for postoperative pain management following spine surgeries. Intravenous opioids are still the primary agents used for perioperative pain control, which can complicate the postoperative recovery with the associated side effects and the risk of opioid dependence. Regional anesthetic techniques for spine surgeries allow rapid recovery, prolonged postoperative analgesia, and less opioid consumption, which decreases hospital stays. The current study will compare the analgesic efficacy of the retrolaminar block to the local wound infiltration following posterior lumbar discectomy surgeries.

Conditions

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Analgesia Disk Herniated Lumbar Local Infiltration

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Retrolaminar block group

After confirming the correct position using imaging with a C-Arm device, the patient will receive a retrolaminar block on both sides at the level of the operated disc.

Group Type ACTIVE_COMPARATOR

Retrolaminar plane block

Intervention Type PROCEDURE

Retrolaminar plane infiltration with the local anesthetic mixture.

Local Infiltration group

The patient will receive local wound infiltration following the completion of the surgical steps with the patient in the prone position using a local anesthetic solution, tailored to the specific conditions surrounding the incision site.

Group Type ACTIVE_COMPARATOR

Local wound infiltration

Intervention Type PROCEDURE

Local infiltration along the surgical incision.

Interventions

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Retrolaminar plane block

Retrolaminar plane infiltration with the local anesthetic mixture.

Intervention Type PROCEDURE

Local wound infiltration

Local infiltration along the surgical incision.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Elective surgical decompression of single-level herniated lumbar disc.

Exclusion Criteria

* Opioid-dependent patients.
* Known hypersensitivity to bupivacaine.
* Diabetic patients.
* Uncooperative patient or with altered mental status.
* Previous spine surgery.

Minimum Eligible Age

21 Years

Maximum Eligible Age

64 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No