Outcomes of Posterior Urethral Valve Fulguration

NCT ID: NCT06867263

Last Updated: 2025-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

35 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-05-01

Study Completion Date

2027-07-01

Brief Summary

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To evaluate the long-term outcome after fulguration of the posterior urethral valve.

Detailed Description

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Posterior Urethral Valves (PUV) are the most common cause of lower urinary tract obstruction. More severe forms are detected early in pregnancy (mainly type I), while other forms are usually discovered later in childhood when investigating lower urinary tract symptoms. Bladder dysfunction is common and is associated with urinary incontinence in about 55% (0%-72%). Despite the removal of the obstruction by urethral valve ablation, pathological changes in the urinary tract can occur with progressive bladder dysfunction, which can cause deterioration of the upper urinary tract as well. For this reason, all children with PUV require long-term follow-up, always until puberty. In many cases, the life-long current status is uncertain. The current literature lacks research on long-term outcomes.

Conditions

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Posterior Urethral Valve

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Fulguration

Posterior urethral valve fulguration

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with fulguration of PUV since 1 year or more

Exclusion Criteria

* Patients with neurogenic bladder or meningocele or spina bifida .

Patients with renal parenchymal disease and inflammation not related to posterior urethral valve .

Diabetic patients .

Parental refusal .
Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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keroles Ashraf Soliman

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Keroles Ashraf Soliman Eskaros Dr

Role: CONTACT

+201061875665

References

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Hennus PM, de Kort LM, Bosch JL, de Jong TP, van der Heijden GJ. A systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys. PLoS One. 2014 Feb 20;9(2):e85474. doi: 10.1371/journal.pone.0085474. eCollection 2014.

Reference Type BACKGROUND
PMID: 24586242 (View on PubMed)

Malin G, Tonks AM, Morris RK, Gardosi J, Kilby MD. Congenital lower urinary tract obstruction: a population-based epidemiological study. BJOG. 2012 Nov;119(12):1455-64. doi: 10.1111/j.1471-0528.2012.03476.x. Epub 2012 Aug 24.

Reference Type BACKGROUND
PMID: 22925164 (View on PubMed)

Other Identifiers

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Posterior urthral valve

Identifier Type: -

Identifier Source: org_study_id

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