Exploring the Influence of Trptophan on the Treatment of Pouchitis
NCT ID: NCT06861140
Last Updated: 2025-03-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
20 participants
INTERVENTIONAL
2025-04-01
2027-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Placebo
regular treatment of pouchitis with consecutive application of antibiotics and probiotics, followed by placebo.
Placebo
standard treatment of chronic pouchitis using pro- and antibiotics.
Intervention
regular treatment of pouchitis with consecutive application of antibiotics and probiotics, additional supplementation of tryptophan (25mg/kg bodyweight)
Tryptophan 25mg/kg bodyweight
Tryptophan is supplemented during the treatment of chronic pouchitis with pro- and antibiotics
Interventions
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Tryptophan 25mg/kg bodyweight
Tryptophan is supplemented during the treatment of chronic pouchitis with pro- and antibiotics
Placebo
standard treatment of chronic pouchitis using pro- and antibiotics.
Eligibility Criteria
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Inclusion Criteria
* indication for the application of antibiotics and probiotics
* Age \>=18 years
* Informed consent
Exclusion Criteria
* high risk for malnutrition (NRS 2002 \>=3/ BMI \<18,5 kg/m\^2)
18 Years
ALL
No
Sponsors
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Universitätsklinikum Hamburg-Eppendorf
OTHER
Responsible Party
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Principal Investigators
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Samuel Huber, Prof. Dr. med.
Role: PRINCIPAL_INVESTIGATOR
Universitätsklinkum Hamburg-Eppendorf, I. Medizinische Klinik und Poliklinik
Central Contacts
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Other Identifiers
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Intramural funding
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
2025-101427-BO-ff
Identifier Type: -
Identifier Source: org_study_id
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