A Combined Supplementation of Rosemary and Daylily for Enhancing Sleep Quality in Middle-Aged Adults

NCT ID: NCT06859879

Last Updated: 2026-01-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-04-15

Study Completion Date

2025-12-15

Brief Summary

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This study aims to investigate the impact of supplementation with two different doses of Rosemary and Daylily herbal extract on various health outcomes in middle-aged adults. Over an eight-week period, the trial will assess improvements in sleep quality, circadian rhythms, energy metabolism, and relevant biochemical markers. The study employs a randomized, placebo-controlled, crossover design to evaluate the efficacy of these supplements in enhancing overall health and well-being.

Detailed Description

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Conditions

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Sleep

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Experimental 1: Low-dose

One capsule of active Rosemary and Daylily extract and one placebo capsule

Group Type EXPERIMENTAL

Dietary Supplement: low-dose Rosemary and Daylily extract

Intervention Type DIETARY_SUPPLEMENT

Supplement containing Rosemary and Daylily extract

Experimental 2: Medium-dose

Two capsules of active Rosemary and Daylily extract

Group Type EXPERIMENTAL

Dietary Supplement: medium-dose Rosemary and Daylily extract

Intervention Type DIETARY_SUPPLEMENT

Supplement containing Rosemary and Daylily extract

Experimental 3: Control

Two capsules of placebo

Group Type PLACEBO_COMPARATOR

Dietary Supplement: control

Intervention Type DIETARY_SUPPLEMENT

Supplement containing placebo

Interventions

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Dietary Supplement: low-dose Rosemary and Daylily extract

Supplement containing Rosemary and Daylily extract

Intervention Type DIETARY_SUPPLEMENT

Dietary Supplement: medium-dose Rosemary and Daylily extract

Supplement containing Rosemary and Daylily extract

Intervention Type DIETARY_SUPPLEMENT

Dietary Supplement: control

Supplement containing placebo

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Age \> 50 years
* Trouble falling asleep \> 5 times a month (NHANES criteria)
* Body mass index 18.5-29.9 kg/m2
* Free of major chronic diseases or acute disorders
* Given written informed consent

Exclusion Criteria

* History of dietary supplement use \> 2 weeks before the study commences
* Abnormal values for lab clinical chemistry (\> 2 SD)
* Unwillingness to return for follow-up analysis
* Participation in other clinical trials
* Moderate-to-heavy use of alcohol (\> 3 drinks per week)
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Novi Sad, Faculty of Sport and Physical Education

OTHER

Sponsor Role lead

Responsible Party

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Sergej Ostojic

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Applied Bioenergetics Lab at Faculty of Sport and PE

Novi Sad, Vojvodina, Serbia

Site Status

Countries

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Serbia

Other Identifiers

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51-02-18

Identifier Type: -

Identifier Source: org_study_id

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