Predictors of Clinical and Neurological Outcome in Traumatic Posterior Fossa Epidural Hematoma

NCT ID: NCT06847516

Last Updated: 2025-02-26

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 94 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-03-01
• Study Completion Date: 2026-05-01

Brief Summary

The posterior fossa is a small space in the skull containing the brainstem and cerebellum. If a mass such as a hemorrhage grows in this region, particularly the brainstem and 4th ventricle, it can block the normal flow of cerebral spinal fluid leading to hydrocephalus, increased intracranial pressure.Posterior fossa extradural hematoma (PFEDH) is a rare neurosurgical entity, resulting in rapid clinical deterioration. The accumulation of blood in a potentially small space between the dura and occipital bone cause compression of the brain stem.These hematomas constitute almost 4% to 12.9% of all extradural hematoma cases.

The extradural hematomas of the posterior fossa may be categorized as acute or delayed defined with respect to the brainstem compression appearing within or after 24 hours of injury, respectively. Acute PFEDH is characterized by medullar failure, occipital trauma associated with severe pain in the nuchal area, altered consciousness followed by rapid brainstem compression, respiratory depression, and subsequent death if not treated timely and appropriately.Whereas, headache, neck pain, dysfunction of lower cranial nerve in response to PF lesions and cerebellar signs. The clinical features of PFEDH are nonspecific; it may include occipital headache, vomiting due to raised intracranial pressure, and decreased consciousness level leading to death. The skull fractures must be considered as a predisposing factor for the development of delayed extradural hematomas.

The aim of this study is :

• To evaluate the outcome of patients with traumatic post fossa Epidural hematoma
• list the predictors of outcome for patients with post fossa Epidural hematoma

Conditions

Posterior Fossa Epidural Hematoma

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Group A

patients admitted to Neurosurgery department withTraumatic Posterior fossa epidural hematoma

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Any age
• Traumatic Posterior fossa epidural hematoma

Exclusion Criteria

• Spontaneous type of epidural heamatoma

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Helal sayed ali

residant doctor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

clinical +NeurologicalPFEH

Identifier Type: -

Identifier Source: org_study_id