Novel Targets for the Development of Monoclonal Antibodies for Immunotherapy)

NCT ID: NCT06842407

Last Updated: 2025-02-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-01

Study Completion Date

2026-06-30

Brief Summary

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The first objective of the project consists in the preclinical validation of new possible molecular targets associated with intratumoral T regulatory cells. The second objective consists in the selection of monoclonal antibodies with therapeutic potential, specific for the selected targets.

Detailed Description

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Conditions

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Healthy Donors

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Healthy Donors

subjects over 18 years of age

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* blood donors
* age of 18 years or more
* able to sign informed consent

Exclusion Criteria

* age below 18 years
* Positive for HIV, HCV, HBV
* not suitable for blood donation
* not able to understand or sign informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

OTHER

Sponsor Role collaborator

Checkmab S.r.l.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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S.C. Medicina Trasfusionale - Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, , Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Renata M Grifantini, PhD

Role: CONTACT

0039 00660220

Facility Contacts

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Daniele Prati, MD

Role: primary

0039 0255034687

Other Identifiers

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ID3411

Identifier Type: -

Identifier Source: org_study_id

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