Usage of Orange Peel Extract in Management of Epistaxis

NCT ID: NCT06836102

Last Updated: 2025-02-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-28

Study Completion Date

2025-05-31

Brief Summary

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Efficacy of orange peel extract in treatment of epistaxis in children

Detailed Description

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Formulation of orange peel extract into gel substance and usage of it in local treatment of epistaxis

Conditions

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Epistaxis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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gel of Orange peel extract

usage of gel of Orange peel extract as a local treatment of epistaxis

Group Type ACTIVE_COMPARATOR

Orange

Intervention Type DIETARY_SUPPLEMENT

usage of orange peel extract in gel layer in treatment of epistaxis

nano-based gel of Orange peel extract

usage of nano-based gel of Orange peel extract as a local treatment of epistaxis

Group Type ACTIVE_COMPARATOR

Orange

Intervention Type DIETARY_SUPPLEMENT

usage of orange peel extract in gel layer in treatment of epistaxis

placebo

usage of placebo in control cases

Group Type PLACEBO_COMPARATOR

Orange

Intervention Type DIETARY_SUPPLEMENT

usage of orange peel extract in gel layer in treatment of epistaxis

Interventions

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Orange

usage of orange peel extract in gel layer in treatment of epistaxis

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* children with anterior epistaxis from little's area

Exclusion Criteria

* patient with nasal polyp.
* patients with hematological abnormalities.
* patients with general diseases affecting coagulation system.
Minimum Eligible Age

5 Years

Maximum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Minia University

OTHER

Sponsor Role lead

Responsible Party

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Mostafa Nasr Zayed

lecturer of otorhinolaryngology Minia university

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Mostafa Nasr Ahmed, consultant

Role: CONTACT

+201007905656

Hanaa Bahaa El-khouly, consultant of pharmacognosy

Role: CONTACT

+201001616758

References

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Andrade MA, Barbosa CH, Shah MA, Ahmad N, Vilarinho F, Khwaldia K, Silva AS, Ramos F. Citrus By-Products: Valuable Source of Bioactive Compounds for Food Applications. Antioxidants (Basel). 2022 Dec 25;12(1):38. doi: 10.3390/antiox12010038.

Reference Type BACKGROUND
PMID: 36670900 (View on PubMed)

Study Documents

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Document Type: Study Protocol

View Document

Related Links

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Other Identifiers

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orange peel in epistaxis

Identifier Type: -

Identifier Source: org_study_id

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