Comparison of 30-day Morbidity and Mortality in Cancer Patients Based on Emergency Department Location

NCT ID: NCT06834646

Last Updated: 2026-01-20

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 2000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-04-12
• Study Completion Date: 2026-09-30

Brief Summary

Patients being followed for cancer account for 2.8% of emergency admissions in France. An acute episode that triggers a visit to the emergency department may be related to the progression of the disease, or to complications of treatment. The management of these patients is often complex and requires a degree of expertise. Emergency departments specialising in the management of cancer complications have been set up, and now deal exclusively with patients treated at their centres. However, for geographical or logistical reasons, patients with cancer are likely to consult a non-specialist emergency department and/or one located outside the cancer care centre. In this case, the emergency doctor may not have access to the oncology file, and care in the emergency department and downstream services may be sub-optimal. Studies have shown a positive impact on the quality of care and prognosis of patients thanks to the cancer centre's expertise. However, the effect of the centre on a cancer patient who visits the emergency department has never been studied. This is particularly true if the emergency department where the patient is seen is located in the cancer follow-up centre.

The primary objective of the COVER study is to investigate the impact of the location of the emergency department where the patient is seen for their prognosis.

Conditions

Cancer; Cancer Remission

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Patients who visit the ED of the refereing oncologic hospital

No interventions assigned to this group

Patients who visit another ED

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

Patients aged 18 or over admitted to an emergency department with cancer that has been active or in remission for less than a year.

Exclusion Criteria

• Opposition to participate in the study

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Hôpital Pitié Salpêtrière Emergency department

Paris, , France

Site Status: RECRUITING

Countries

France

Central Contacts

Yonathan FREUND, PU-PH

Role: CONTACT

yonathan.freund@aphp.fr

00 33 (0) 184827129

Olivier PEYRONY, MD, PhD

Role: CONTACT

olivier.peyrony@aphp.fr

00 33 (0) 142494939

Other Identifiers

IDRCB: 2024-A01679-38

Identifier Type: OTHER

Identifier Source: secondary_id

APHP240971

Identifier Type: -

Identifier Source: org_study_id