Multi-disciplinary Care for Brain Metastases

NCT ID: NCT06280300

Last Updated: 2026-01-29

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-11-16
• Study Completion Date: 2027-07-01

Brief Summary

This is a health services intervention study aimed at understanding the impact of intensive multi-disciplinary care compared with standard care on patient-reported symptom outcomes and prognostic awareness in patients with brain metastases.

Detailed Description

This is a cohort study of patient with newly diagnosed brain metastases assigned to standard of care (SOC) or intensive multi-disciplinary care (IMDC). Care for all patients with brain metastases involves complex medical decision making and requires input for multiple stakeholders, including medical oncology, neurosurgery, radiation oncology, and neuro-oncology. Palliative care should be an essential component of the care team for all patients with brain metastases by the very nature of this advanced malignancy. At the University of Vermont, our current process for diagnosis and management of patients with brain metastases relies heavily on the physician and team who make the initial diagnosis to consult others as they see appropriate. This process may look different for different patients. We rationalize that a systematic approach with intensive multidisciplinary care (IMDC) will benefit patients with brain metastases by providing consistent access to multi-disciplinary discussion.

Conditions

Brain Metastases, Adult

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: HEALTH_SERVICES_RESEARCH
• Blinding Strategy: NONE

Study Groups

Standard of Care

Group Type: ACTIVE_COMPARATOR

health services intervention

Intervention Type: OTHER

Health services intervention

Multidisciplinary Care

Group Type: EXPERIMENTAL

health services intervention

Intervention Type: OTHER

Health services intervention

Interventions

health services intervention

Health services intervention

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patients of all genders must be at least 18 years of age.
• Patients must have histologically confirmed, newly diagnosed brain metastases from known or suspected solid tumor primary neoplasms.
• Patients must be able to accurately provide self-report data (e.g. per clinical judgment, cognitive function is intact).
• Patients must be able to complete questionnaires in English.
• Patients must have the ability to provide informed consent.

Exclusion Criteria

• Patients who are < 18 years of age are not eligible.
• Patients who are Pregnant are not eligible.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of Vermont Medical Center

OTHER

Sponsor Role: lead

Responsible Party

Alissa Thomas

Associate Professor of Neurological Sciences

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

University of Vermont Medical Center

Burlington, Vermont, United States

Site Status: RECRUITING

Countries

United States

Central Contacts

Alissa A Thomas, MD

Role: CONTACT

athoma21@med.uvm.edu

802-847-8400

Other Identifiers

UVMMC2203

Identifier Type: -

Identifier Source: org_study_id