Development of a Personalized Growth Hormone Treatment Profile (PGTP) Report for Pediatric Endocrinology

NCT ID: NCT06830525

Last Updated: 2025-12-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-05-19

Study Completion Date

2025-11-12

Brief Summary

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The goal of this observational study is to learn how to make growth hormone treatment more personalized for children. The main questions it aims to answer are:

* How can information about treatment adherence and patient experiences help improve care?
* What insights can help doctors create treatment plans that are more tailored to each child?

The study will include 40 families of children who are using a connected injector device for their growth hormone treatment. These devices track how often the treatment is taken, and families will also share their experiences through surveys. The information will be used to develop a new tool, similar to tools used in diabetes care, to help doctors create better, personalized treatment plans for children with growth hormone needs.

Detailed Description

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Conditions

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Growth Hormone Deficiency (GHD)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Families with children undergoing growth hormone treatment

The study targets families of children with growth hormone deficiency (GHD) under growth hormone treatment, using a connected injector device that quantifies treatment adherence. We will recruit 40 families, divided into two groups: one group with adherence rates of \<85%, and the other group with adherence rates of \>85%.

ACDP® and growth hormone treatment

Intervention Type COMBINATION_PRODUCT

A cohort of 40 families of children undergoing growth hormone treatment using a connected injector devices that quantifies treatment adherence will be recruited via the ACDP®, to capture additional data that combine Patient Reported Outcomes and Adherence Data.

Interventions

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ACDP® and growth hormone treatment

A cohort of 40 families of children undergoing growth hormone treatment using a connected injector devices that quantifies treatment adherence will be recruited via the ACDP®, to capture additional data that combine Patient Reported Outcomes and Adherence Data.

Intervention Type COMBINATION_PRODUCT

Eligibility Criteria

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Inclusion Criteria

* Pediatric patients (up to 18 years old) diagnosed with growth hormone deficiency or disorders requiring growth hormone treatment.
* Patients are currently undergoing growth hormone therapy. Includes both naive patients (those newly starting weekly treatment) and those already on treatment.
* Families willing to use connected injector devices and participate in mobile-based psychometrics for the study duration.
* Families are able and willing to regularly provide patient-reported outcomes (PROs) and adherence data through the Adhera®️ Caring Digital Program.
* Participants willing to sign the informed consent form, confirming their understanding of the essential aspects of the study, including the potential risks, benefits and rights as participants.

Exclusion Criteria

* Families/patients already enrolled in other study protocols, including the use of connected injector devices and participation in mobile-based psychometrics.
* Patients with other significant medical conditions that could interfere with growth hormone treatment or the study's data collection processes.
* Inability to understand or communicate in the language used for data collection and study participation, unless appropriate translation services are available and can be consistently utilized.
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hospital Miguel Servet

OTHER

Sponsor Role collaborator

Luis Fernandez Luque

INDUSTRY

Sponsor Role lead

Responsible Party

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Luis Fernandez Luque

Chief Scientific Officer

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Hospital Universitario Miguel Servet

Zaragoza, Aragon, Spain

Site Status

Countries

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Spain

Other Identifiers

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PGTP

Identifier Type: -

Identifier Source: org_study_id

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