Effect of Bathing on Physiological Parameters, Skin, Bilirubin and Comfort Levels in Infants Receiving Phototherapy

NCT ID: NCT06819150

Last Updated: 2025-02-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-05-01

Study Completion Date

2025-03-15

Brief Summary

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The aim of this study is to determine the effect of bathing on physiological parameters (heart rate, body temperature and oxygen saturation), skin, bilirubin and comfort level in infants receiving phototherapy.

Detailed Description

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Neonatal jaundice (hyperbilirubinemia) causes a yellowish discolouration of the sclera and skin due to increased levels of bilirubin in the blood. Jaundice develops in 60% of term babies and 80% of premature babies in the first week of life. Currently, the appropriate treatment option for neonatal jaundice is phototherapy. Phototherapy treatment reduces bilirubin concentrations through various photochemical reactions that allow bilirubin to be excreted more easily. However, phototherapy treatment is associated with short-term side effects including transient skin rashes, diarrhoea, hyperthermia and dehydration.

Physiological reasons such as the weak connection between the epidermis and dermis layer in the skin of the newborn, the pH value of the skin being close to neutral or alkaline, and the low melanosome production increase the susceptibility of the newborn to infection and skin damage. Invasive interventions, use of antiseptics, phototherapy and various instruments may disrupt the skin integrity of the newborn. Therefore, all newborns receiving treatment and care in the neonatal intensive care unit are at risk in terms of skin integrity.

In the majority of newborn infants; jaundice develops, which can affect the newborn neurologically, motor and hearing if left untreated,. Phototherapy devices are widely used today for the treatment of jaundice. Phototherapy devices used in the treatment of jaundice have side effects such as skin rashes, diarrhea, dehydration and hyperthermia. In the literature reviewed, results were found that bathing the newborn reduces phototherapy rashes, lowers the bilirubin level and increases the comfort of the newborn. Also in the literature; There are studies showing that one of the most suitable bathing methods for a newborn is bathtub bathing and that bathing with baby shampoo is not harmful to the newborn.

Conditions

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Phototherapy Skin Rash

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Newborn bathing

The term and preterm infants in the experimental group will have a bathtub bath before starting phototherapy treatment.

Group Type EXPERIMENTAL

Newborn bathing

Intervention Type OTHER

The babies in the experimental group will have a bathtub bath before starting phototherapy treatment.

Standard of care

No intervention other than routine clinical practices will be applied to the control group.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Newborn bathing

The babies in the experimental group will have a bathtub bath before starting phototherapy treatment.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Born at 35-41 gestational weeks
* Indirect hyperbilirubinaemia diagnosed at 24 hours of birth or more,
* No health problems,
* Indication for phototherapy treatment
* Stable vital signs
* Whose parents agreed to participate in the study

Exclusion Criteria

* Newborns with ABO and Rh incompatibility,
* Direct diagnosis of hyperbilirubinaemia,
* Congenital anomaly,
* With skin lesions
Minimum Eligible Age

1 Day

Maximum Eligible Age

28 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Selcuk University

OTHER

Sponsor Role lead

Responsible Party

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Raziye Çelen

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Perihan B Çalışkan, MSc student

Role: PRINCIPAL_INVESTIGATOR

Selcuk University

Raziye Çelen, Asst. Prof.

Role: PRINCIPAL_INVESTIGATOR

Selcuk University

Locations

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Kütahya Şehir Hospital

Kütahya, Merkez, Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Perihan B Çalışkan, MSc student

Role: CONTACT

+90 5061626224 ext. +90 5061626224

Raziye Çelen, Asst. Prof.

Role: CONTACT

+90 0332 241 01 10

Facility Contacts

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Perihan B Çalışkan, MSc student

Role: primary

+90 506 162 6224 ext. +90 5061626224

Raziye Çelen, Asst. Prof.

Role: backup

+90 0332 241 01 10

Other Identifiers

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2023/78_TR

Identifier Type: -

Identifier Source: org_study_id

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