BREAST Choice Decision Tool R21 - AIM2

NCT ID: NCT06817226

Last Updated: 2025-11-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-10

Study Completion Date

2026-08-28

Brief Summary

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Breast reconstruction is a critical component of breast cancer treatment because it restores quality of life and body image after mastectomy. However, Spanish-speaking Latina women are significantly less likely to undergo reconstruction (13.5% vs. 41% for non-Latina White or highly acculturated Latina), meet with a reconstructive surgeon (18.1% vs. 72.6% for non-Latina White), or receive adequate information. Spanish-speaking Latina breast cancer survivors who do not have reconstruction experience the highest rates of decisional dissatisfaction and regret, compared to any other group of breast cancer survivors.

Persons diagnosed with cancer who primarily speak Spanish and identify as Latin American (hereafter we use the term "Spanish-speaking Latinx/a cancer survivor") are less likely to receive guideline-concordant treatment and more likely to have poor cancer outcomes. One way to improve guideline-concordant treatment is through shared decision-making and decision support. When a decision is preference-sensitive (the right choice depends on the person's preferences), such as decisions about breast reconstruction after mastectomy, decision aids are effective. Unfortunately, most decision aids in the United States are written in English and developed or tested with few Latinx people.

The BREASTChoice decision aid, proven effective in two randomized controlled trials, addresses knowledge gaps in breast cancer survivors. This study focuses on developing a Spanish-language version of BREASTChoice, which was previously unavailable. For that reason, the Cultural and Linguistic Adaptation Framework (CLAF) incorporates qualitative and experiential data to adapt BREASTChoice. The adaptation process takes place in five steps: appraise, review, assess, solicit, and integrate.

Detailed Description

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Conditions

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Breast Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Breast cancer survivors

Latina breast cancer survivors.

Group Type OTHER

Pre-survey

Intervention Type BEHAVIORAL

Participants will take a pre-survey to measure demographics, health literacy, numeracy and breast reconstruction decision quality.

BREASTChoice tool.

Intervention Type BEHAVIORAL

Participants will then engage in a self-guided review of the adapted BREASTChoice tool.

Post-survey

Intervention Type BEHAVIORAL

Participants will take the post-survey to assess breast reconstruction decision quality.

Interventions

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Pre-survey

Participants will take a pre-survey to measure demographics, health literacy, numeracy and breast reconstruction decision quality.

Intervention Type BEHAVIORAL

BREASTChoice tool.

Participants will then engage in a self-guided review of the adapted BREASTChoice tool.

Intervention Type BEHAVIORAL

Post-survey

Participants will take the post-survey to assess breast reconstruction decision quality.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Female sex
* Adult at least 18 years of age
* Latina, Latino, or Latinx ethnicity - defined as born in or descending from South America, Mexico, Central America, other Spanish-speaking Caribbean islands
* Prefer to receive health information in Spanish
* Have a history of breast malignancy (e.g., ductal carcinoma, DCIS) or high risk for breast cancer (e.g., BRCA mutation)
* Had breast surgery (Mastectomy/Lumpectomy/Mastectomy but no reconstruction) within the last 8 years
* Able to understand an IRB-Approved consent information sheet

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

UNC Lineberger Comprehensive Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clara Lee, MPP, MD

Role: PRINCIPAL_INVESTIGATOR

UNC Lineberger Comprehensive Cancer Center

Locations

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The University of North Carolina

Chapel Hill, North Carolina, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Victor Catalan Gallegos

Role: CONTACT

+1 919-966-3215

Meaghan Hazelet

Role: CONTACT

919-966-4320

Facility Contacts

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Meaghan Hazelet

Role: primary

919-966-4320

Related Links

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Other Identifiers

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R21CA287321

Identifier Type: NIH

Identifier Source: secondary_id

View Link

24-1340 - AIM2

Identifier Type: -

Identifier Source: org_study_id

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