SWEtick - a Prospective Multicenter Study of Tick-borne Diseases in Sweden
NCT ID: NCT06781008
Last Updated: 2025-06-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
500 participants
OBSERVATIONAL
2023-09-01
2035-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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TBD
Patients with confirmed tick-borne disease
No interventions assigned to this group
Non-TBD
Patients investigated for suspected tick-borne disease but diagnosed with another condition (tick-borne disease excluded)
No interventions assigned to this group
Control group CNS
Patients obtaining spinal anasthesia in conjunction with knee or hip replacement surgery due to arthrosis
No interventions assigned to this group
Control group arthritis
Patients with autoinflammatory joint disease
No interventions assigned to this group
Control group healthy
Blood donors
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
1 Year
ALL
Yes
Sponsors
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Region Östergötland
OTHER
Region Kalmar County
UNKNOWN
Region Dalarna
UNKNOWN
FORSS - The Research Council of South-Eastern Sweden
UNKNOWN
ALF Grants, Region Östergötland
UNKNOWN
Linkoeping University
OTHER_GOV
Anna J Henningsson
OTHER_GOV
Responsible Party
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Anna J Henningsson
Senior Consultant, Senior Associate Professor
Locations
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Department of Paediatrics, Eksjö Hospital
Eksjö, Region Jönköping County, Sweden
Department of Infectious Diseases, County Hospital Ryhov
Jönköping, Region Jönköping County, Sweden
Department of Infectious Diseases, Kalmar County Hospital
Kalmar, Region Kalmar County, Sweden
Department of Infectious Diseases, Linköping University Hospital
Linköping, Region Östergötland, Sweden
Department of Infectious Diseases, Vrinnevi Hospital
Norrköping, Region Östergötland, Sweden
Department of Paediatrics, Vrinnevi Hospital
Norrköping, Region Östergötland, Sweden
Countries
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Central Contacts
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Facility Contacts
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References
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Henningsson AJ, Asgeirsson H, Hammas B, Karlsson E, Parke A, Hoornstra D, Wilhelmsson P, Hovius JW. Two Cases of Borrelia miyamotoi Meningitis, Sweden, 2018. Emerg Infect Dis. 2019 Oct;25(10):1965-1968. doi: 10.3201/eid2510.190416.
Uhnoo I, Cars O, Christensson D, Nystrom-Rosander C. First documented case of human babesiosis in Sweden. Scand J Infect Dis. 1992;24(4):541-7. doi: 10.3109/00365549209052642.
Eimer J, Fernstrom L, Rohlen L, Grankvist A, Loo K, Nyman E, Henningsson AJ, Haglund M, Hultqvist V, Sjowall J, Wenneras C, Schon T. Spiroplasma ixodetis Infections in Immunocompetent and Immunosuppressed Patients after Tick Exposure, Sweden. Emerg Infect Dis. 2022 Aug;28(8):1681-1685. doi: 10.3201/eid2808.212524.
Bjoersdorff A, Berglund J, Kristiansen BE, Soderstrom C, Eliasson I. [Varying clinical picture and course of human granulocytic ehrlichiosis. Twelve Scandinavian cases of the new tick-borne zoonosis are presented]. Lakartidningen. 1999 Sep 29;96(39):4200-4. Swedish.
Nilsson K, Elfving K, Pahlson C. Rickettsia helvetica in patient with meningitis, Sweden, 2006. Emerg Infect Dis. 2010 Mar;16(3):490-2. doi: 10.3201/eid1603.090184.
Nilsson K, Lindquist O, Pahlson C. Association of Rickettsia helvetica with chronic perimyocarditis in sudden cardiac death. Lancet. 1999 Oct 2;354(9185):1169-73. doi: 10.1016/S0140-6736(99)04093-3.
Wenneras C, Wass L, Bergstrom B, Grankvist A, Lingblom C. Ten years of detecting Neoehrlichia mikurensis infections in Sweden: demographic, clinical and inflammatory parameters. Eur J Clin Microbiol Infect Dis. 2024 Nov;43(11):2083-2092. doi: 10.1007/s10096-024-04909-5. Epub 2024 Aug 13.
Quarsten H, Henningsson A, Krogfelt KA, Strube C, Wenneras C, Mavin S. Tick-borne diseases under the radar in the North Sea Region. Ticks Tick Borne Dis. 2023 Jul;14(4):102185. doi: 10.1016/j.ttbdis.2023.102185. Epub 2023 Apr 26.
Henningsson AJ, Aase A, Bavelaar H, Flottorp S, Forsberg P, Kirkehei I, Lovmar M, Nilsson K, Nyman D, Ornstein K, Sjowall J, Skogman BH, Tjernberg I, Aaberge I. Laboratory Methods for Detection of Infectious Agents and Serological Response in Humans With Tick-Borne Infections: A Systematic Review of Evaluations Based on Clinical Patient Samples. Front Public Health. 2021 Sep 20;9:580102. doi: 10.3389/fpubh.2021.580102. eCollection 2021.
Related Links
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General study information and contact details
Other Identifiers
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EPM 2022-05330-01
Identifier Type: -
Identifier Source: org_study_id
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