CardioMEMS HF System Coverage with Evidence Development Study

NCT ID: NCT06779552

Last Updated: 2025-02-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-02-07

Study Completion Date

2032-03-31

Brief Summary

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The purpose of the CardioMEMS CED Study is to determine if pulmonary artery (PA) pressure-guided heart failure management using the CardioMEMS™ HF System improves long-term health outcomes in heart failure (HF) patients in the real-world setting.

Detailed Description

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The CardioMEMS CED Study will assess 2-year HF hospitalization rates and survival for all-cause mortality in heart failure subjects managed with the CardioMEMS HF system, as compared to a contemporaneous control of HF subjects managed without PA pressure-guidance.

Conditions

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Heart Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Treatment Group

Heart failure patients implanted with the CardioMEMS PA pressure sensor.

CardioMEMS HF System

Intervention Type DEVICE

PA Pressure Sensor

Control Group

Heart failure patients being managed without PA pressure-monitoring.

No interventions assigned to this group

Interventions

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CardioMEMS HF System

PA Pressure Sensor

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Subject implanted with a CardioMEMS pressure sensor (treatment arm only)
2. Subject \>=18 years of age at time of implant
3. Subject has a history of acute decompensated HF or HF-related congestion defined by at least one of the following qualifying event types: HF hospitalization, elevated BNP/NT-proBNP

Exclusion Criteria

1. Subject has history of heart transplant or durable mechanical circulatory device
2. Subject hospitalized with cardiogenic shock or sepsis
3. Subject received prior PA pressure sensor implant (control arm only)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott Medical Devices

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Abbott

Pleasanton, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Nessa Johnson

Role: CONTACT

612-283-3865

Facility Contacts

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Nessa Johnson

Role: primary

612-283-3865

Other Identifiers

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CL1027482

Identifier Type: -

Identifier Source: org_study_id

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