The Impact of Lumboscopy Versus Laparoscopy on Ventilatory Mechanics

NCT ID: NCT06776068

Last Updated: 2025-01-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-02-01

Study Completion Date

2026-03-30

Brief Summary

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There are several techniques for performing minimally invasive urological surgeries. Among them, laparoscopic surgery, robotic surgery, and lumboscopy are noteworthy (1). The medical literature extensively documents the impact of pneumoperitoneum a procedure involving the insufflation of the peritoneal cavity with carbon dioxide (CO2), which is essential for laparoscopic and robotic surgeries on ventilatory mechanics.

As an alternative, CO2 insufflation into the retroperitoneum, as utilized in lumboscopic surgery, has been proposed. This approach is believed to exert a lesser impact on respiratory function and pulmonary mechanics. However, it is important to note that no conclusive evidence has yet been found to support this claim.

Assessing the impact of lumboscopic surgery could help establish it as a viable alternative for patients with pulmonary conditions, where mechanical ventilation poses significant challenges. To explore this possibility, a physiological study was designed to compare the effects of laparoscopic and lumboscopic surgery on ventilatory mechanics.

Detailed Description

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Conditions

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Anesthesia Mechanical Ventilation Respiratory Physiology

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Adult patients undergoing general anesthesia for laparoscopic and lumboscopic nephrectomy

Adult patients undergoing general anesthesia for laparoscopic and lumboscopic nephrectomy.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age \>18 years old
* ASA PS II-III
* Elective surgery
* Surgery: Partial or total nephrectomy

Exclusion Criteria

* Severe pulmonary pathology
* Severe cardiovascular pathology
* Open surgery
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Chile

OTHER

Sponsor Role lead

Responsible Party

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Roberto Gonzalez Cornejo

Anesthesiologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Hospital Clínico Universidad de CHile

Santiago, , Chile

Site Status

Instituto Nacional del Cáncer

Santiago, , Chile

Site Status

Countries

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Chile

Central Contacts

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Roberto González, MD

Role: CONTACT

+56999397515

Felipe Maldonado, MD

Role: CONTACT

+56992160831

Facility Contacts

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Roberto González, MD

Role: primary

+56999397515

Felipe Maldonado, MD

Role: backup

+56992160831

Roberto González, MD

Role: primary

+56999397515

Nicolás Valls, PhD, MD

Role: backup

+56933741332

References

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Guillonneau B, Ballanger P, Lugagne PM, Valla JS, Vallancien G. Laparoscopic versus lumboscopic nephrectomy. Eur Urol. 1996;29(3):288-91. doi: 10.1159/000473762.

Reference Type BACKGROUND
PMID: 8740033 (View on PubMed)

Other Identifiers

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CR/23053

Identifier Type: -

Identifier Source: org_study_id

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