Comparison of LASER Therapy and Desensitizing Agents in Dentinal Hypersensitivity

NCT ID: NCT06759454

Last Updated: 2025-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

172 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-06-30

Study Completion Date

2026-06-30

Brief Summary

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This study evaluates the effectiveness of laser therapy versus desensitizing agents in reducing pain among participants with dentinal hypersensitivity conducted in Saidu College of Dentistry. Pain will be measured at baseline, immediately post-treatment, one week, and three months using the Visual Analog Scale (VAS)

Detailed Description

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This study examines dentinal hypersensitivity treatment modalities, including laser therapy and desensitizing agents. The study is conducted in compliance with regional ethical guidelines

Conditions

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Dentinal Hypersensitivity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Arm 1 (Desensitizing Agent)

A glutaraldehyde-based desensitizing agent applied to affected teeth for 30 seconds, air-dried, with post-application instructions

Group Type ACTIVE_COMPARATOR

Glutaraldehyde-Based Desensetizing Agent

Intervention Type DRUG

A glutaraldehyde-based desensitizing agent applied to the cervical area of affected teeth using a micro-brush, left undisturbed for 30 seconds, and air-dried. Both interventions aim to reduce pain associated with dentinal hypersensitivity by either occluding dentinal tubules or reducing nerve excitability

Arm 2 (Laser Therapy)

Diode laser set to 100 mW in continuous wave mode, applied to specific areas of affected teeth for three minutes

Group Type EXPERIMENTAL

Low Level Laser Therapy

Intervention Type DEVICE

Low-level laser therapy (LLLT) using a diode laser set to a low power level (e.g., 100 mW, continuous wave mode). Each affected tooth will be treated for three minutes, targeting apical, cervical, and middle points

Interventions

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Glutaraldehyde-Based Desensetizing Agent

A glutaraldehyde-based desensitizing agent applied to the cervical area of affected teeth using a micro-brush, left undisturbed for 30 seconds, and air-dried. Both interventions aim to reduce pain associated with dentinal hypersensitivity by either occluding dentinal tubules or reducing nerve excitability

Intervention Type DRUG

Low Level Laser Therapy

Low-level laser therapy (LLLT) using a diode laser set to a low power level (e.g., 100 mW, continuous wave mode). Each affected tooth will be treated for three minutes, targeting apical, cervical, and middle points

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Participants aged 18-50 years with a preoperative VAS score of ≥2 for dentinal hypersensitivity.
* Participants with sensitivity due to gingival recession, cervical abrasion, or enamel erosion.
* Participants with good systemic health.
* Minimum of two hypersensitive teeth present in two different quadrants.

Exclusion Criteria

* Teeth with caries, defective restorations, or cervical defects \> 2 mm (may affect sensitivity measurements).
* Periodontal surgery or deep periodontal pockets (\> 6 mm) within the past three months (potential influence on periodontal health and sensitivity).
* Participants using desensitizing toothpaste within the past three months (could interfere with study outcomes).
* Presence of gross oral pathology or systemic diseases (e.g., eating disorders, chronic diseases, uncontrolled metabolic conditions) (may alter oral health status).
* Pregnant or lactating women (hormonal changes can influence oral health).
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kemia Gul

OTHER

Sponsor Role lead

Responsible Party

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Kemia Gul

Comparison of Mean Pain Score Using Laser Therapy and Desensitizing Agents in Patients with Dentinal Hypersensitivity: A Randomized Controlled Trial

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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BREKHNA YOUSAFZAI

Role: PRINCIPAL_INVESTIGATOR

Saidu College of Dentistry

Locations

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Saidu College of Dentistry

Swat, KPK, Pakistan

Site Status

Countries

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Pakistan

Central Contacts

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Brekhna Yousafzai

Role: CONTACT

+923417262127

Kemia Gul

Role: CONTACT

+923352803890

Facility Contacts

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Saidu College of Dentistry Saidu Sharif Swat

Role: primary

009469240142

Other Identifiers

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208-ERB/024

Identifier Type: -

Identifier Source: org_study_id

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