Cardiac Magnetic Resonance Predictors of Outcome of Rhythm Control in Patients with Atrial Fibrillation/Flutter

NCT ID: NCT06758895

Last Updated: 2025-01-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-31

Study Completion Date

2026-05-31

Brief Summary

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evaluate the impact of various features in CMR on the mid-term/long-term success rate of rhythm control for paroxysmal atrial fibrillation/flutter .

Detailed Description

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* Atrial fibrillation/flutter are widely prevalent.
* Reported antiarrhythmic drug efficacy to restore \& maintain sinus rhythm is 52% which is far from optimal.
* On the other hand, 5-year arrhythmia-free survival after catheter ablation was previously reported to be 63%.
* Therefore, there is a need for better characterization of the underlying atrial substrate, to improve treatment outcomes in terms of efficacy and safety

Conditions

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Rhythm Monitoring

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age\>18 years.
* Patients undergoing successful cardioversion (pharmacologic or electric) for atrial fibrillation/flutter, OR symptomatic patients with paroxysmal atrial fibrillation/flutter scheduled for trans-catheter ablation.
* Index cardioversion OR Index ablation procedure.

Exclusion Criteria

* LA thrombus on TEE or CMR.
* Contraindications to CMR.
* Contraindications to Gd-based contrast.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Maryam Ashraf Abd El-Naeem Sayed

Resident Doctor at Assiut University Heart Hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Salah EL-dein Sayed Ata, Professor of cardiology

Role: STUDY_DIRECTOR

Assiut University

Locations

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Assiut Univeristy Heart Hospital

Asyut, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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Maryem Ashraf Abd El-Naeem Sayed, Resident Doctor

Role: CONTACT

+2001097400995

Amr EL-Badry Ibrahim, Lecture of cardiology

Role: CONTACT

+2001060701601

References

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1. Calkins H et al. Circ Arrhythm Electrophysiol. 2009

Reference Type BACKGROUND

Other Identifiers

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CMR in rythm control

Identifier Type: -

Identifier Source: org_study_id

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