Mangement of Pulmonary Emboli

NCT ID: NCT06756373

Last Updated: 2025-01-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-20

Study Completion Date

2027-12-17

Brief Summary

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To assess to which extent we are adherent to ESC guidelines 2019 in management of patients presented with acute pulmonary embolism

Detailed Description

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Pulmonary embolism (PE) is the third most frequent cardiovascular disease and is associated with a high mortality burden PE is defined as the obstruction of a pulmonary artery, mostly resulting from the dislodgement of thrombotic material from the lower limbs. It has a wide variety of presentations, ranging from an asymptomatic incidental finding to circulatory collapse and sudden death Pulmonary embolism response teams (PERTs) have emerged as a multidisciplinary team for managing acute pulmonary embolism, with a rapid activation process for multimodality assessment, risk stratification and best management especially for complex challenge cases. PERTs help in improving time to PE diagnosis; shorter time to initiation of anticoagulation reducing hospital length of stay, increasing use of advanced therapies as catheter directed therapies without an increase in bleeding complications with decreasing mortality

Conditions

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Pulmonary Embolism (Diagnosis)

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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To assess to which extent we are adherent to ESC guidelines 2019 in management of patients presented

Comparing ESC 2019 criteria for risk stratification and mortality with new scores \[BOVA , modified FAST, PEITHO-3 models \& POPE\].

-Comparing management and outcomes of in hospital and 30 days follow up of pulmonary embolism before and after starting PERT in our center

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* No includion criteria
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Rania Abdelmoaz Farghaly

resident doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Rania Abdelmoaz Farghaly, master student

Role: CONTACT

+201284742238

References

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Gerardo F, Faria D, Silverio Antonio P, Baltazar Ferreira J, Beringuilho M, Ferreira H, Fialho I, Miranda I, Sa Pereira Y, Nunes-Ferreira A, Roque D, Santos MB, Morais C, Bravo Baptista S, Augusto JB. PrOgnosis in Pulmonary Embolism (PoPE): 30-Day mortality risk score based on five admission parameters. Rev Port Cardiol. 2024 Jan;43(1):1-8. doi: 10.1016/j.repc.2023.04.011. Epub 2023 Jul 7. English, Portuguese.

Reference Type BACKGROUND
PMID: 37423312 (View on PubMed)

Leidi A, Bex S, Righini M, Berner A, Grosgurin O, Marti C. Risk Stratification in Patients with Acute Pulmonary Embolism: Current Evidence and Perspectives. J Clin Med. 2022 Apr 30;11(9):2533. doi: 10.3390/jcm11092533.

Reference Type BACKGROUND
PMID: 35566658 (View on PubMed)

Cohen AT, Agnelli G, Anderson FA, Arcelus JI, Bergqvist D, Brecht JG, Greer IA, Heit JA, Hutchinson JL, Kakkar AK, Mottier D, Oger E, Samama MM, Spannagl M; VTE Impact Assessment Group in Europe (VITAE). Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality. Thromb Haemost. 2007 Oct;98(4):756-64. doi: 10.1160/TH07-03-0212.

Reference Type BACKGROUND
PMID: 17938798 (View on PubMed)

ISTH Steering Committee for World Thrombosis Day. Thrombosis: a major contributor to the global disease burden. J Thromb Haemost. 2014 Oct;12(10):1580-90. doi: 10.1111/jth.12698.

Reference Type BACKGROUND
PMID: 25302663 (View on PubMed)

Other Identifiers

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mangement of pulmonary emboli

Identifier Type: -

Identifier Source: org_study_id

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