Urinary Infection in Pregnant Women with Urinary Infection

NCT ID: NCT06752161

Last Updated: 2025-02-04

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 224 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-02-01
• Study Completion Date: 2027-01-31

Brief Summary

Urine analysis and culture in patients with threatened preterm labour

Detailed Description

UTI is an infection of the kidneys, bladder, or urethra. Infectious cystitis is the most common type of UTI, which is caused by a bacterial infection of the bladder. Lifetime incidence of UTIs is 50% to 60% in adult women.UTIs are among the most common conditions encountered in primary care, hospitals, and extended care facilities . Total direct costs of UTI treatment (without cultures) have been estimated at US $25.5 billion annually.Despite an exceptionally high prevalence of bacteriuria in the population, these infections rarely cause significant renal damage.Sexual intercourse is the strongest risk factor. Any lifetime sexual activity and any sexual activity during the past year are strongly associated with recurrent UTI. Even the relatively small amounts of spermicide coating condoms increases the risk of UTI. Post-menopausal absence of oestrogen is a risk factor for UTIs. Topical oestrogen reduces UTIs in post-menopausal women; Oestrogenisation of the vaginal mucosa promotes lactobacilli colonisation, which reduces the presence of uropathogens and thus the risk of UTIs and is not recommended over the use of topical oestrogen therapy. Urinary incontinence and oestrogen supplementation have also been associated with UTI in older women, although the reasons for this are incompletely understood. positive family history of UTIs is associated with a two- to fourfold increase in risk of recurrent UTI . Bacteriuria occurs in the presence of indwelling or intermittent catheters, and asymptomatic bacteriuria does not require treatment. Gestational and pregestational diabetes are considered a more predominant risk factor in older women.

Conditions

Threatened Preterm Labour

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Pregnant women with threatened preterm labour

Patients with UTI and preterm labour

Urine analysis

Intervention Type: OTHER

Urine analysis and culture for Screening and diagnostic tools for UTI in pregnant women

Interventions

Urine analysis

Urine analysis and culture for Screening and diagnostic tools for UTI in pregnant women

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• pregnant women with preterm labor

Exclusion Criteria

• renal disease Intrauterine fetal death

• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Mohamed Gamal M.fekry

Lecturer of obstetric and gynecology, specialist of Uro gynecology

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Mohammed Seif al nasr, MBBCH

Role: PRINCIPAL_INVESTIGATOR

Women's Health Hospital Resident

Locations

Women's Health Hospital

Asyut, , Egypt

Site Status: RECRUITING

Countries

Egypt

Central Contacts

Mohamed Fekry, PhD

Role: CONTACT

mohamedbeethoven2040@gmail.com

0882312388

Facility Contacts

Women Hospital

Role: primary

ethics_committee12@yahoo.com

0882414916

Other Identifiers

UTIP

Identifier Type: -

Identifier Source: org_study_id