Short-term Immunomodulatory Effects of Lactobacillus Casei DN-114001: Impacts on Gut Microbiota Composition and Systemic Immune Biomarkers in Healthy Adults

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

21 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-02-01

Study Completion Date

2013-09-30

Brief Summary

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The study included 21 adult participants, aged 19-46 years (19 female participants and 2 male participants). The selection criteria included the following parameters: Body Mass Index (BMI), calculated as weight (kg) divided by height squared (m²), between 18.5 and 29.99; Waist-to-Hip Ratio with thresholds set at \>0.90 for males and \>0.85 for females for individuals with normal weight (eutrophic); percentage of body fat: Considered within normal range if \<30% for individuals with normal weight. Standard biochemical and anthropometric measurements were carried out to all the subjects.

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Detailed Description

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Conditions

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Immune Modulation

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Sequential intervention

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Intervention group

Healthy subjects

Group Type EXPERIMENTAL

Lactobacillus casei DN-114001

Intervention Type DIETARY_SUPPLEMENT

Probiotic

Interventions

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Lactobacillus casei DN-114001

Probiotic

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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Actimel

Eligibility Criteria

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Inclusion Criteria

* Body Mass Index (BMI) between 18.5 and 29.99;
* Waist-to-Hip Ratio with thresholds set at \>0.90 for males and \>0.85 for females for individuals with normal weight (eutrophic)
* Percentage of body fat: Considered within normal range if \<30% for individuals with normal weight.

Minimum Eligible Age

19 Years

Maximum Eligible Age

46 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes