Cardiac RadiothErapy for VEntricular Tachycardia II

NCT ID: NCT06744530

Last Updated: 2025-01-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-01

Study Completion Date

2034-12-31

Brief Summary

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Steoreotactic therapy radioablation has become a standard of care option for patients with therapy-refractory ventricular tachycardia, yet long-term outcome is lacking. The objective of this study is to evaluate the long-term outcomes, both efficacy and safety, after STAR in patients with therapy-refractory ventricular tachycardia.

Detailed Description

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Conditions

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Ventricular Tachycardia (VT)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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stereotactic radiotherapy ablation

Single dose of 25 Gy up to 32.5 Gy on the myocardium in patients with therapy-refractory ventricular tachycardia

Intervention Type PROCEDURE

Other Intervention Names

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STAR stereotactic body radiotherapy

Eligibility Criteria

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Inclusion Criteria

* Eligible for STAR for therapy-refractory VT based on a multidisciplinary discussion
* Ability to give a written informed consent and willingness to return for follow-up

Exclusion Criteria

* Contra-indications for STAR, including pregnancy or breastfeeding, previous radiotherapy with cardiac involvement, life-expectancy \< 6 months in the absence of VT
* Any condition that is deemed a contraindication in the judgment of the investigators
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitaire Ziekenhuizen KU Leuven

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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UZ Leuven

Leuven, , Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Bert Vandenberk, MD PhD

Role: CONTACT

+3216338686

Patrick Berkovic, MD PhD

Role: CONTACT

Facility Contacts

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Bert Vandenberk, MD PhD

Role: primary

+3216338686

Other Identifiers

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S69812

Identifier Type: -

Identifier Source: org_study_id

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