The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery
NCT ID: NCT06743802
Last Updated: 2025-02-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE4
264 participants
INTERVENTIONAL
2025-01-09
2026-03-20
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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Coenzyme Q10
Coenzyme Q10
Coenzyme Q10 was administered from admission to one month after discharge at a dose of 200 mg per day (200 mg/qd).
Placebo
Placebo
The placebo was administered from hospital admission until one month after discharge.
Interventions
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Coenzyme Q10
Coenzyme Q10 was administered from admission to one month after discharge at a dose of 200 mg per day (200 mg/qd).
Placebo
The placebo was administered from hospital admission until one month after discharge.
Eligibility Criteria
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Inclusion Criteria
* American Society of Anesthesiology (ASA) physical status classification I-III;
* Scheduled for elective lung resection surgery under thoracoscopy;
* Voluntarily opting for patient-controlled intravenous analgesia;
* Willing to participate in this trial after consultation with the patient or their family and signing the informed consent form.
Exclusion Criteria
* Patients converted to open thoracotomy intraoperatively;
* Severe hepatic or renal dysfunction;
* History of substance abuse;
* Pregnancy or breastfeeding;
* History of chronic pain;
* Use of coenzyme Q10 for more than one month;
* Allergy to coenzyme Q10;
* Patients unable to communicate or cooperate.
18 Years
75 Years
ALL
No
Sponsors
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The Second Affiliated Hospital of Chongqing Medical University
OTHER
Responsible Party
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Locations
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Guangyou Duan
Chongqing, Chongqing Municipality, China
Countries
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Central Contacts
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Facility Contacts
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References
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Liu J, Li L, Luo L, Wu N, Xu F, Tao C, Chen J, Huang H, Duan G. Effect of coenzyme Q10 on pain prevention after thoracoscopic surgery: study protocol. Pain Manag. 2025 Sep 30:1-8. doi: 10.1080/17581869.2025.2567832. Online ahead of print.
Other Identifiers
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Coenzyme Q10 and pain
Identifier Type: -
Identifier Source: org_study_id
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