Collaborate and Leverage Evidence in African American Rural Network

NCT ID: NCT06730633

Last Updated: 2026-02-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

173 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-22

Study Completion Date

2026-05-31

Brief Summary

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The goal of this non-randomized, propensity-matched-controlled study is to assess the effectiveness of the Heart Matters evidence-based program -- previously evaluated for feasibility and efficacy in NCT02707432 -- in improving cardiovascular health outcomes (change in systolic and diastolic blood pressure, primary outcomes) when implemented by community-based facilitators.

Detailed Description

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The research team will use a non-randomized, propensity-matched-controlled design to evaluate the effectiveness of the Heart Matters evidence-based program -- previously evaluated for feasibility and efficacy under NCT02707432 -- in improving cardiovascular health outcomes when scaled in multiple rural, eastern North Carolina counties and implemented by community-based facilitators.

This study aims to recruit 210 participants, 70 of whom will be propensity-score-matched with participants from NCT02707432. Propensity-score-matching will allow for flexibility in recruitment, statistical rigor, and resource efficiency. The research team hypothesizes that matched participants in the present study will show significant improvements in health outcomes (systolic blood pressure, diastolic blood pressure) compared to the matched NCT02707432 controls.

Conditions

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Cardiovascular Diseases

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Non-randomized, propensity-matched-controlled trial. Specifically, 70 participants from the present study will be propensity-matched with 70 participants from NCT02707432.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Intervention Group

This group will receive the Heart Matters intervention, delivered by community-based facilitators. All participants consenting to the present study will be assigned to this arm.

Group Type EXPERIMENTAL

Heart Matters

Intervention Type BEHAVIORAL

Heart Matters is a lifestyle modification intervention guided by the theory of planned behavior. Designed to mitigate cardiovascular disease risk factors, the program strives to help participants consume nutritious foods, engage in a more active lifestyle, lose weight and lower their systolic or diastolic blood pressure. Lifestyle modifications can include weight loss, a reduction in percent calorie fat consumption and total sodium intake, improving diet and increasing physical activity, and reducing daily alcoholic beverage consumption.

Propensity-matched Control Group (Retrospective)

This group received the Heart Matters intervention, delivered by researchers, under NCT02707432.

Group Type ACTIVE_COMPARATOR

Heart Matters

Intervention Type BEHAVIORAL

Heart Matters is a lifestyle modification intervention guided by the theory of planned behavior. Designed to mitigate cardiovascular disease risk factors, the program strives to help participants consume nutritious foods, engage in a more active lifestyle, lose weight and lower their systolic or diastolic blood pressure. Lifestyle modifications can include weight loss, a reduction in percent calorie fat consumption and total sodium intake, improving diet and increasing physical activity, and reducing daily alcoholic beverage consumption.

Interventions

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Heart Matters

Heart Matters is a lifestyle modification intervention guided by the theory of planned behavior. Designed to mitigate cardiovascular disease risk factors, the program strives to help participants consume nutritious foods, engage in a more active lifestyle, lose weight and lower their systolic or diastolic blood pressure. Lifestyle modifications can include weight loss, a reduction in percent calorie fat consumption and total sodium intake, improving diet and increasing physical activity, and reducing daily alcoholic beverage consumption.

Intervention Type BEHAVIORAL

Other Intervention Names

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PREMIER

Eligibility Criteria

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Inclusion Criteria

* Identify as Black or African American
* Reside in rural, eastern North Carolina
* Self-report at least one cardiovascular disease risk factor, such as pre-diabetes, pre-hypertension or stage one hypertension, obesity, or family history of early heart disease

Exclusion Criteria

* Evidence of active or unstable cardiovascular disease
* Cognitive impairment that limits informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Heart, Lung, and Blood Institute (NHLBI)

NIH

Sponsor Role collaborator

Project Momentum, Inc.

INDUSTRY

Sponsor Role collaborator

James McFarlin Community Development, Inc.

OTHER

Sponsor Role collaborator

Opportunities Industrialization Center, Inc.

UNKNOWN

Sponsor Role collaborator

University of North Carolina, Chapel Hill

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Gaurav Dave, MBBS, DrPH

Role: PRINCIPAL_INVESTIGATOR

University of North Carolina, Chapel Hill

Locations

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A Better Chance, A Better Community

Enfield, North Carolina, United States

Site Status

The Mercer Foundation, Inc.

Nashville, North Carolina, United States

Site Status

Marks Chapel Baptist Church

Rocky Mount, North Carolina, United States

Site Status

Thorne's Chapel Missionary Baptist Church

Rocky Mount, North Carolina, United States

Site Status

Truth Tabernacle Ministries

Rocky Mount, North Carolina, United States

Site Status

Girls Making the Grade

Rocky Mount, North Carolina, United States

Site Status

Carolina Hierarchy of Needs

Spring Hope, North Carolina, United States

Site Status

St. James United Holy Church

Stantonsburg, North Carolina, United States

Site Status

Warren County Health Department

Warrenton, North Carolina, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Informed Consent Form

View Document

Other Identifiers

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5R01HL157255

Identifier Type: NIH

Identifier Source: secondary_id

View Link

21-1366

Identifier Type: -

Identifier Source: org_study_id

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