A Real-world Study on the Treatment of Non-small Cell Lung Cancer With Leptomeningeal Metastasis in China

NCT ID: NCT06718972

Last Updated: 2025-04-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-01

Study Completion Date

2028-12-31

Brief Summary

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This is a retrospective and prospective study planned to include NSCLC patients with Leptomeningeal metastasis (LM) and treated with antitumor therapy after 2018, from multiple centers such as the First Affiliated Hospital of Guangzhou Medical University, Guangdong Sanjiu Brain Hospital, etc., aiming to establish a database related to the treatment strategies of LM patients, and to evaluate the efficacy (eg. Overall Survival/Time to Failure) and safety of different treatment strategies of LM patients, etc., as well as the significance of concomitant testing in LM patients.

Detailed Description

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retrospective and prospective study

Conditions

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Meningeal Metastasis Non-Small Cell Lung Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Interventions

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Not applicable- observational study

This is a retrospective and observational study. Not Applicable

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* non-small cell lung cancer patients with Leptomeningeal metastases diagnosed after January 2018;
* Patients who underwent antitumor therapy after diagnosis of LM.

Exclusion Criteria

* Patients with small cell lung cancer components;
* complicated with tumors other than non-small cell lung cancer.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Guangzhou Medical University

OTHER

Sponsor Role lead

Responsible Party

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Haihong Yang, MD, Pricipal investigator

Chief Physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Guangdong Sanjiu Brain Hospital

Guangzhou, Guangdong, China

Site Status RECRUITING

the First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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hong hai Yang

Role: CONTACT

13711244230

Facility Contacts

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chief physician

Role: primary

chief physician

Role: primary

13711244230

Other Identifiers

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ES-2024-K125-02

Identifier Type: -

Identifier Source: org_study_id

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