CTC in Lung Caner Patients With Bone Metastases

NCT ID: NCT04568291

Last Updated: 2021-08-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

160 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-10-01

Study Completion Date

2022-12-31

Brief Summary

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1. Evaluate the feasibility of single cell sequencing technology based on three-dimensional bionic capture network;
2. To build a risk prediction model of bone related events based on single cell sequencing;
3. To verify the risk prediction model of bone related events by single cell sequencing;
4. To verify the comprehensive treatment of non-small cell lung cancer ( NSCLC) bone metastases.

Detailed Description

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Conditions

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Lung Cancer Bone Metastases Single Cell Sequencing Technology

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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routine treatment

routine treatment

Group Type ACTIVE_COMPARATOR

routine treatment

Intervention Type OTHER

the treatment decisions were decided by multi-disciplinary team (MDT)

model treatment

model treatment

Group Type EXPERIMENTAL

model treatment

Intervention Type OTHER

the treatment decisions were decided by Machine Learning (ML) model in model treatment group

Interventions

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model treatment

the treatment decisions were decided by Machine Learning (ML) model in model treatment group

Intervention Type OTHER

routine treatment

the treatment decisions were decided by multi-disciplinary team (MDT)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. age 18-75 years
2. pathology-proven diagnosis of lung cancer and radiographical/pathological evidence of BM
3. no previous treatment for BM
4. good general condition (Eastern Cooperative Oncology Group, ECOG Performance scores: 0-2) with an estimated survival time \> 3 months.

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai 6th People's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Zhao Hui

Clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Shanghai Sixth People'S Hospital

Shanghai, Other (Non U.s.), China

Site Status RECRUITING

Countries

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China

Facility Contacts

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hui zhao

Role: primary

13564460369

Other Identifiers

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CTC01

Identifier Type: -

Identifier Source: org_study_id

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