Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
141 participants
OBSERVATIONAL
2024-01-01
2024-09-01
Brief Summary
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Besides Obstructive Sleep Apnea measures are rapidly evolving and conventional measures such as apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) are increasingly being supplemented by measures of hypoxia such as hypoxic burden.
Residual AHI in treated OSA have limited predictive value for objective sleepiness. Therefore it seems particularly relevant to identify other predictors of both subjective and objective sleepiness.
This study aims at studying the influence of hypoxic burden as measure of both subjective or objective sleepiness.
We hypothesize that impaired nocturnal oxygenation might influence brain functioning during wakefulness and result in sleepiness as assessed by ESS and MWT.
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Hypoxic burden and Sleepiness in treated OSA patients
In this retrospective study, we reviewed the files of all patients with OSA hospitalised to undergo both polysomnography (PSG) and the 40-min MWT in the Center for Sleep Medicine and Respiratory Disease, Lyon Academic Hospital from September 2017 to January 2020.
All these patients underwent a full night polysomnography.
Impact of hypoxic burden on objective and subjective sleepiness in patients treated for Obstructive Sleep apnea
To determine whether hypoxic load is a predictive marker of objective residual sleepiness measured by MCT in a treated OSAHS population.
Interventions
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Impact of hypoxic burden on objective and subjective sleepiness in patients treated for Obstructive Sleep apnea
To determine whether hypoxic load is a predictive marker of objective residual sleepiness measured by MCT in a treated OSAHS population.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* refusal to participate in the study
* diagnosis of central disorder of hypersomnolence
* missing data on the MWT
* Epworth Sleepiness Scale (ESS)
* apnea-hypopnea index (AHI).
18 Years
ALL
No
Sponsors
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Hospices Civils de Lyon
OTHER
Responsible Party
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Principal Investigators
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Dr Pierre TANKERE, MD, Msc
Role: PRINCIPAL_INVESTIGATOR
Service de médecine du sommeil et des maladies respiratoires Hôpital de la Croix-Rousse
Locations
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Service de médecine du sommeil et des maladies respiratoires Hôpital de la Croix-Rousse
Lyon, , France
Countries
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Other Identifiers
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23-5474
Identifier Type: -
Identifier Source: org_study_id
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