Evaluation of the Venous Excess Ultrasound Score (VExUS) After Circulating Volume Modification in Children.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

67 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-12-10

Study Completion Date

2025-06-06

Brief Summary

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Venous overload has an impact on peripheral organ perfusion and on the short- and long-term prognosis of intensive care patients. The VExUS ultrasound score is a new tool whose parameters can be used to estimate this impact. This score was initially evaluated and validated on an adult population. ) In children, there is only one study looking at the use and applicability of this VExUS score, highlighting its feasibility in a paediatric population, as well as a possible correlation between elevated central venous pressure and altered renal Doppler (one of the score's components).

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Detailed Description

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Conditions

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Blood Volume Expansion

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Experimental

Patients over one year of age treated at Toulouse University Hospital and receiving extrarenal purification, bloodletting or vascular filling \> 10 ml/kg.

VExUS evaluation ultrasound

Intervention Type OTHER

VExUS evaluation by ultrasound will be performed before the filling/bleeding/cleaning procedure, and again after the procedure:

* Inferior vena cava measurement in Time-Motion (TM) mode, 1-2 cm from the right atrial orifice.
* Hepatic venous Doppler measurement in pulsed Doppler mode.
* Renal vein Doppler measurement in pulsed Doppler mode. Each measurement is performed three times consecutively (to average the results), then the ultrasound measurements are compiled into a score according to the degree of doppler severity.

Interventions

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VExUS evaluation ultrasound

VExUS evaluation by ultrasound will be performed before the filling/bleeding/cleaning procedure, and again after the procedure:

* Inferior vena cava measurement in Time-Motion (TM) mode, 1-2 cm from the right atrial orifice.
* Hepatic venous Doppler measurement in pulsed Doppler mode.
* Renal vein Doppler measurement in pulsed Doppler mode. Each measurement is performed three times consecutively (to average the results), then the ultrasound measurements are compiled into a score according to the degree of doppler severity.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Children aged between 1 and 18 years, receiving extrarenal purification with UF \> 10 ml/kg, bleeding \> 10 ml/kg or vascular filling \> 10 ml/kg

Exclusion Criteria

* Refusal of the patient or opposition of one or both holders of parental authority.
* Minors with parental authority.
* Ultrafiltration time \> 6h.
* Curarized patient, known abnormality of the hepatorenal venous network.
* Patient agitated or poor tolerance of the examination.
* Parents under court protection, guardianship or curatorship.

Minimum Eligible Age

1 Year

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No