Intravascular Radiofrequency Ablation of Sympathetic Nerves for the Treatment of Hepatocellular Carcinoma

NCT ID: NCT06694636

Last Updated: 2024-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

5 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-02-01

Study Completion Date

2026-02-01

Brief Summary

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Patients who met the inclusion criteria were treated with endovascular radiofrequency ablation and desympathetic nerve surgery. After enrollment, endovascular radiofrequency ablation and desympathetic surgery were performed. After radiofrequency ablation, the safety and efficacy of follow-up treatment will be carried out every 1 month or so, including blood routine, liver and kidney function, tumor indicators, abdominal CT/magnetic resonance, etc.

Detailed Description

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Conditions

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Hepatocellular Carcinoma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Enrolled patients will receive intravascular Radiofrequency Ablation of Sympathetic Nerves for the Treatment of Hepatocellular Carcinoma
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Intravascular Radiofrequency Ablation of Sympathetic Nerves Group

Enrolled patients will receive Intravascular Radiofrequency Ablation of Sympathetic Nerves for the Treatment of Hepatocellular Carcinoma

Group Type EXPERIMENTAL

endovascular radiofrequency ablation and desympathetic nerve surgery

Intervention Type PROCEDURE

endovascular radiofrequency ablation and desympathetic nerve surgery

Interventions

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endovascular radiofrequency ablation and desympathetic nerve surgery

endovascular radiofrequency ablation and desympathetic nerve surgery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Clinically or pathologically confirmed hepatocellular carcinoma (HCC)
* Locally progressed or distant metastatic unresectable advanced HCC
* Progressed after second-line therapy
* Agree to participate in the study and sign the informed consent form

Exclusion Criteria

* Not suitable for ablation surgery
* Pregnant, lactating and planning to become pregnant
* Orthostatic hypotension
* Mixed liver cancer
* Intestinal obstruction
* Obvious bleeding tendencies and hematologic diseases
* Acute or severe systemic infection;
* Stroke or transient ischemic attack (TIA) within two weeks;
* Acute coronary syndrome within two weeks;
* Evaluated to be not suitable for this trial by investigators
Minimum Eligible Age

25 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zhongda Hospital

OTHER

Sponsor Role lead

Responsible Party

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Gao-jun Teng

Director of Interventional and Vascular Surgery Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gao-Jun Gao-Jun

Role: PRINCIPAL_INVESTIGATOR

Zhongda Hospital

Locations

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Zhongda Hospital

Nanjing, Jiangsu, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Hai-Dong Zhu

Role: CONTACT

+86-25-83272121

Teng

Role: CONTACT

Facility Contacts

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Teng Gaojun

Role: primary

86-02583272121

Other Identifiers

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2024ZDSYLL167-P01

Identifier Type: -

Identifier Source: org_study_id

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