New Approach for Ovarian PRP Injection for Poor Responders

NCT ID: NCT06663930

Last Updated: 2024-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

21 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-01

Study Completion Date

2025-06-30

Brief Summary

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New Approach For Ovarian PRP Injection for poor responders

Detailed Description

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Poor ovarian responders are at high risk of unsuccessful IVF/ICSI trials. In the last few years, many studies showed significant improvement of ovarian reserve parameters after PRP injection. There was no consensus regarding the route of injection, the volume injected, the location of PRP injection inside the ovary, the number of injection and the number of the cycle in which PRP is injected.

Conditions

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Poor Responders

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* AMH : \< 0.5 ng/ml
* FSH: \> 10 miu but \< 25 miu.
* AFC : \< 5 in both ovaries
* Poor ovarian response, in a previous IVF/ICSI trial , resulting in 3 or fewer oocytes.
* Normal uterine cavity , demonstrated by a recent hysteroscopy

Exclusion Criteria

* Primary ovarian insufficiency with FSH \> 25 miu.
* Previous ovarian surgery or Chemotherapy.
* On going Anticoagulant use.
* Carcinomas or a history of chronic pelvic pain.
* Present infection.
* Hemoglobin level lower than 11 g/L
* platelet count lower than 150 x 10³/μL.
Minimum Eligible Age

30 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Bassem Ayman Mahmoud Assaf

OTHER

Sponsor Role lead

Responsible Party

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Bassem Ayman Mahmoud Assaf

Medical Doctor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Benha University

Banhā, benha, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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New Approach For Ovarian PRP

Identifier Type: -

Identifier Source: org_study_id

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