Outcome-related Performance Evaluation Through Revision and Analysis of inTraoperative Events

NCT ID: NCT06655948

Last Updated: 2024-10-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

700 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-10-31

Study Completion Date

2029-10-31

Brief Summary

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The goal of this prospective, multicentric, observational, cohort study is to evaluate intraoperative adverse events (iAEs) through video-based assessment (VBA) across minimal invasive procedures performed in general surgery departments. The main questions it aims to answer are:

* The prevalence, type, and severity of iAEs
* Correlation between iAE and clinical outcomes
* Correlation between iAE and surgical performance
* Qualitative analysis of root cause analysis and mitigation strategies

Detailed Description

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The OPERATE study is a prospective, multicenter observational cohort study focused on evaluating the prevalence and impact of intraoperative adverse events (iAEs) during minimally invasive surgeries. The study aims to systematically collect and analyze surgical videos and clinical outcomes from multiple centers. By using advanced video-based assessment (VBA) tools, such as the Objective Clinical Human Reliability Analysis (OCHRA) and the Severity of Intraoperative Events and Rectification (SEVERE) index, the study will examine how surgical performance correlates with post-operative outcomes.

The study will initially focus on colorectal surgery, with the possibility of expanding to other types of minimally invasive procedures. Videos of the surgeries will be recorded, de-identified, and uploaded to a centralized platform for analysis. The study also seeks to identify root causes of iAEs and develop strategies to prevent them. Data collection will include not only video-based assessments but also patient demographic details, surgical history, and post-operative recovery data.

By understanding the frequency and nature of iAEs, this study aims to improve surgical safety, reduce complications, and ultimately enhance the quality of patient care in a broad range of general surgical procedures. The findings may contribute to developing new training protocols, artificial intelligence instruments to model errors and increase procedural safety, and guidelines to optimize surgical performance and patient outcomes.

Conditions

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Laparoscopic Abdominal Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients scheduled for elective minimally-invasive surgery in participating centers
* Patients with no contraindication to anesthesia and laparoscopic procedures
* Capable of providing informed consent

Exclusion Criteria

* Surgery performed with palliative intent or under unplanned/emergency setting
* Pregnant or breastfeeding patient
* Patient under legal custody or guardianship
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sergio Alfieri

Role: PRINCIPAL_INVESTIGATOR

Fondazione Policlinico Universitario A. Gemelli, IRCCS

Locations

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IHU Strasbourg

Strasbourg, , France

Site Status

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, MI, Italy

Site Status

Ospedale Isola TIberina - Gemelli Isola

Rome, RM, Italy

Site Status

Azienda Ospedaliero-Universitaria Sant'Andrea

Rome, RM, Italy

Site Status

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Rome, RO, Italy

Site Status

Countries

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France Italy

Central Contacts

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Sergio Alfieri, prof

Role: CONTACT

+390630154477

Pietro Mascagni

Role: CONTACT

Facility Contacts

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Nicolas Padoy, Professor

Role: primary

+330390413600

Luigi Boni, Professor

Role: primary

+390250320326

Vincenzo Tondolo, MD

Role: primary

+39066837646

Gianfranco Silecchia, Professor

Role: primary

+390633775607

Sergio Alfieri, Professor

Role: primary

+390630154477

Other Identifiers

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6456

Identifier Type: -

Identifier Source: org_study_id

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