Immediate Effects of High-intensity Laser Therapy on Knee Joint Position Sense and Knee Muscle Strength in Patients with Knee Osteoarthritis

NCT ID: NCT06632119

Last Updated: 2024-10-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-05

Study Completion Date

2024-09-01

Brief Summary

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The goal of this clinical trial is to compare whether HILT versus Sham-HILT is effective to reduce pain, improve knee joint position sense, and knee muscle strength.

Participants will undergo a single-session of HILT or Sham-HILT, the measurements of pain, knee joint position sense error, and knee muscle strength will be done at before, immediately after, and 24-hour after the single-session intervention.

Detailed Description

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The investigators would like to investigate whether single session of high-intensity laser therapy (HILT) is promising to see the changes in individuals with knee osteoarthritis (KOA)-related knee pain regarding pain intensity, knee joint position sense, and knee muscle strength.

The objectives of this study is to compare pre and post, and between the two groups (HILT versus Sham-HILT) at after interventions regarding pain, knee joint position sense, and knee muscle strength.

Participants will undergo a single-session of HILT or Sham-HILT by an experienced musculoskeletal physical therapist, the measurements of pain, knee joint position sense error, and knee muscle strength will be done at before, immediately after, and 24-hour after the single-session intervention.

Conditions

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Knee Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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HILT

high-intensity laser therapy (HILT)

Group Type ACTIVE_COMPARATOR

high-intensity laser therapy

Intervention Type DEVICE

high-intensity laser therapy (HILT) machine, ASA laser

Sham_HILT

Sham-HILT, the HILT without laser release

Group Type PLACEBO_COMPARATOR

Sham-HILT

Intervention Type DEVICE

Sham-HILT, HILT machine without laser release

Interventions

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high-intensity laser therapy

high-intensity laser therapy (HILT) machine, ASA laser

Intervention Type DEVICE

Sham-HILT

Sham-HILT, HILT machine without laser release

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* knee pain greater than 3 on the Visual Analog Scale (VAS) for more than 3 months
* diagnosed with unilateral knee osteoarthritis by a physician or meeting the American College of Rheumatology Classification Criteria for clinical knee osteoarthritis
* the severity of knee osteoarthritis is classified as grades 0-3 according to the Kellgren-Lawrence (KL) classification
* should not have undergone any specific treatments in the 3 months preceding the recruitment for the study, such as steroid injections.

Exclusion Criteria

* any other musculoskeletal problems associated with knee pain
* musculoskeletal problems associated with the hip and ankle joints
* a history of lower limb fracture
* neurological conditions
* contraindications for laser therapy
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mahidol University

OTHER

Sponsor Role lead

Responsible Party

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Prasert Sakulsriprasert

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Prasert Sakulsriprasert, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Mahidol University

Locations

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Physical Therapy

Salaya, Changwat Nakhon Pathom, Thailand

Site Status

Countries

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Thailand

Other Identifiers

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MU_CIRB 2024/003.0401

Identifier Type: -

Identifier Source: org_study_id

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