Outcomes and Prognostic Factors in Hepatopancreatoduodenectomy

NCT ID: NCT06631352

Last Updated: 2024-10-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2000-01-01

Study Completion Date

2024-05-31

Brief Summary

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1. In biliary tract malignancies, achieving a microscopically clear resection margin (R0) is considered the only treatment for a cure.
2. Hepatopancreatoduodenectomy(HPD) has been considered a surgical option for patients with extensive bile duct or gallbladder cancer to achieve an R0 resection.
3. The associated high morbidity and mortality rates have prevented HPD from becoming a standard surgical procedure worldwide.
4. Over the past few decades, the understanding of the bile duct anatomy has significantly improved, and many methods have been developed to assess liver function and future remnant liver volume.
5. We aimed to evaluate the short- and long-term outcomes of HPD and to assess risk factors associated with survival, early recurrence, and major complications to better evaluate the potential of the procedure as a standard treatment.

Detailed Description

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Conditions

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Hepatopancreaticobiliary (HPB) Malignancy Gall Bladder Cancer Bile Duct Cancer Pancreatoduodenectomy Hepatectomy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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GB cancer

Patients who were diagnosed with gallbladder cancer and underwent the hepatopancreatoduodenectomy.

Hepatopancreatoduodenectomy

Intervention Type OTHER

Pancreatoduodenectomy with liver resection

CCA

Patients who were diagnosed with cholangiocarcinoma and underwent the hepatopancreatoduodenectomy.

Hepatopancreatoduodenectomy

Intervention Type OTHER

Pancreatoduodenectomy with liver resection

Interventions

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Hepatopancreatoduodenectomy

Pancreatoduodenectomy with liver resection

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients who received hepatopancreatoduodenectomy between January 2000 and December 2023.

Exclusion Criteria

* Patients who had R2 resection
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jin-Young Jang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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2407-049-1551

Identifier Type: -

Identifier Source: org_study_id

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