Anti-obesity Effects of Dandelion (Taraxacum Officinale L.)

NCT ID: NCT06625736

Last Updated: 2024-10-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-05

Study Completion Date

2024-09-07

Brief Summary

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The study investigates the effectiveness of the natural product Dandelion in treating obesity in premenopausal women through a randomized interventional trial, measuring various parameters and biomarkers.

Detailed Description

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The study aims to explore the anti-obesity effects of dandelion supplementation in premenopausal obese women. The research will measure changes in appetite, energy intake, body weight, composition, lipid profile, and inflammatory markers, providing evidence of dandelion\'s efficacy as an anti-obesity phototherapy. The randomized interventional trial will measure multiple parameters and biomarkers.

Conditions

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Obese Women Perimenopause

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Control group

The Xenical group:60 patients will receive identical capsules of 120mg (one capsule) to be taken three times daily with meals and for 12 weeks, equaling 360mg total daily dose.

Group Type ACTIVE_COMPARATOR

Xenical

Intervention Type DRUG

The Xenical group will receive identical capsules 120mg (one capsule) to be taken three times daily with meals, equaling 360mg total daily dose, which aligns with the usage in adult female patients

The dandelion extract group

The dandelion extract group: 60 patients will receive 500 mg capsules of dandelion leaf extract, given 3 times per day before meals and for 12 weeks.

Group Type EXPERIMENTAL

The dandelion extract

Intervention Type DIETARY_SUPPLEMENT

The dandelion extract group will receive 500 mg capsules of dandelion leaf extract, given 3 times per day before meals.

Interventions

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Xenical

The Xenical group will receive identical capsules 120mg (one capsule) to be taken three times daily with meals, equaling 360mg total daily dose, which aligns with the usage in adult female patients

Intervention Type DRUG

The dandelion extract

The dandelion extract group will receive 500 mg capsules of dandelion leaf extract, given 3 times per day before meals.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

Premenopausal women with obesity. Age between 18-45 years Stable body weight in the past 3 months

Exclusion Criteria

Pregnancy Breastfeeding Diabetes Cardiovascular diseases kidney or liver diseases use of medications that affect body weight Smoking Allergy to dandelion or related plants
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Pharos University in Alexandria

OTHER

Sponsor Role collaborator

October 6 University

OTHER

Sponsor Role lead

Responsible Party

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rabab ahmed mohamed

Principle investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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October 6 University Hospital

Giza, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Dandelion effect on obesity

Identifier Type: -

Identifier Source: org_study_id

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