Pharmacokinetics and Safety Profiles After Administration of DA-5221_01 and Co-administration of 5221_01-R1 and DA-5221_01-R2 in Healthy Adult Volunteers

NCT ID: NCT06616883

Last Updated: 2024-09-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

PHASE1

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-09-30

Study Completion Date

2024-11-18

Brief Summary

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Pharmacokinetics and Safety Profiles After Administration of DA-5221\_01 and Co-administration of 5221\_01-R1 and DA-5221\_01-R2 in Healthy Adult Volunteers

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Experimental: Sequence A

Group Type EXPERIMENTAL

DA-5221_01

Intervention Type DRUG

single dose administration (DA-5221\_01 one tablet once a day)

DA-5221_01-R1 + DA-5221_01-R2

Intervention Type DRUG

single dose administration (DA-5221\_01-R1 one tablet once a day + DA-5221\_01-R2 one tablet once a day)

Experimental: Sequence B

Group Type EXPERIMENTAL

DA-5221_01

Intervention Type DRUG

single dose administration (DA-5221\_01 one tablet once a day)

DA-5221_01-R1 + DA-5221_01-R2

Intervention Type DRUG

single dose administration (DA-5221\_01-R1 one tablet once a day + DA-5221\_01-R2 one tablet once a day)

Interventions

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DA-5221_01

single dose administration (DA-5221\_01 one tablet once a day)

Intervention Type DRUG

DA-5221_01-R1 + DA-5221_01-R2

single dose administration (DA-5221\_01-R1 one tablet once a day + DA-5221\_01-R2 one tablet once a day)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Healthy volunteers
* BMI between 18 and 30 kg/m2
* Body weight: Male≥50kg, Female≥45kg
* Subjects who have signed an informed consent themselves after receiving detailed explanation about clinical study

Exclusion Criteria

* Subjects with clinically significant medical history
* Subjects with history of drug abuse or addicted
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Dong-A ST Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Bumin Hospital

Seoul, South Korea, South Korea

Site Status

Countries

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South Korea

Central Contacts

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Sung

Role: CONTACT

Phone: +82-02-920-8369

Email: [email protected]

Jung

Role: CONTACT

Phone: +82-02-920-8361

Email: [email protected]

Facility Contacts

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TaeGon Hong, Ph.D

Role: primary

Other Identifiers

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DA5221_01_BE_I

Identifier Type: -

Identifier Source: org_study_id