Pharmacokinetics and Safety Following Administration of DWP16001

NCT ID: NCT05414591

Last Updated: 2022-07-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

38 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-01

Study Completion Date

2021-08-01

Brief Summary

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To compare and evaluate the safety and pharmacokinetic characteristics after administration of DWP16001 Drug A and DWP16001 Drug B in healthy adult volunteers

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Sequence group A

DWP16001 A mg 1T

Group Type EXPERIMENTAL

DWP16001 drug A

Intervention Type DRUG

1 tablet, Oral, once daily single dose

DWP16001 drug B

Intervention Type DRUG

3 tablet, Oral, once daily single dose

Sequence group B

DWP16001 B mg 3T

Group Type EXPERIMENTAL

DWP16001 drug A

Intervention Type DRUG

1 tablet, Oral, once daily single dose

DWP16001 drug B

Intervention Type DRUG

3 tablet, Oral, once daily single dose

Interventions

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DWP16001 drug A

1 tablet, Oral, once daily single dose

Intervention Type DRUG

DWP16001 drug B

3 tablet, Oral, once daily single dose

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Healthy adult volunteers aged ≥ 19 years at screening
* Subjects with a body weight of ≥ 50.0 kg to ≤ 90.0 kg with a body mass index (BMI) of ≥ 18.0 kg/m2 and ≤ 30.0 kg/m2
* Subjects with no congenital or chronic disease that requires treatment, and no clinical symptoms or findings based on medical examination
* Subjects who are determined eligible to participate in this study based on results of laboratory tests, vital signs, physical examination etc at screening.

Exclusion Criteria

* Current or history of clinically significant hepatic, renal, nervous, respiratory, endocrine, hemato-oncology, cardiovascular, urogenital, psychosis disorder
* Current or history of gastrointestinal disorders or prior history of gastrointestinal surgery that may affect safety and PK/PD assessment of the study drug
* Clinical laboratory test values are outside the accepted normal range at screening
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Daewoong Pharmaceutical Co. LTD.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHA Bundang Medical Center, CHA University

Seongnam-si, Gyeonggi-do, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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DW_DWP16001105

Identifier Type: -

Identifier Source: org_study_id

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