Phenotypes of Preschool Wheezing Among Children Attending Sohag University Hospital
NCT ID: NCT06603584
Last Updated: 2024-09-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
100 participants
OBSERVATIONAL
2024-06-04
2025-04-04
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
RETROSPECTIVE
Study Groups
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group A
Bronchial Asthma
Chest x- Rays
prebronchial Thicknening - Right upper lobe Patches suggesting Aspiration -Collapsing lobe
group B
Chronic Aspiration
Chest x- Rays
prebronchial Thicknening - Right upper lobe Patches suggesting Aspiration -Collapsing lobe
group C
Primary Ciliary Dyskinesia
Chest x- Rays
prebronchial Thicknening - Right upper lobe Patches suggesting Aspiration -Collapsing lobe
group D
Cystic Fibrosis
Chest x- Rays
prebronchial Thicknening - Right upper lobe Patches suggesting Aspiration -Collapsing lobe
Interventions
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Chest x- Rays
prebronchial Thicknening - Right upper lobe Patches suggesting Aspiration -Collapsing lobe
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Failure to obtain informed consent.
* Children below 6 years with chest diseases other than wheezing
2 Years
6 Years
ALL
No
Sponsors
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Sohag University
OTHER
Responsible Party
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Amr Ahmed Gamal Eldin
Resident-pediatric department-sohag hospital university
Locations
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Sohag university Hospital
Sohag, , Egypt
Countries
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Central Contacts
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Mostfa A Mohammed, assistant professor
Role: CONTACT
Facility Contacts
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Magdy M Amin, professor
Role: primary
References
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Fitzpatrick AM, Bacharier LB, Guilbert TW, Jackson DJ, Szefler SJ, Beigelman A, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Zeiger RS, Mauger DT; NIH/NHLBI AsthmaNet. Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation. J Allergy Clin Immunol Pract. 2019 Mar;7(3):915-924.e7. doi: 10.1016/j.jaip.2018.09.016. Epub 2018 Sep 26.
Lowe LA, Simpson A, Woodcock A, Morris J, Murray CS, Custovic A; NAC Manchester Asthma and Allergy Study Group. Wheeze phenotypes and lung function in preschool children. Am J Respir Crit Care Med. 2005 Feb 1;171(3):231-7. doi: 10.1164/rccm.200406-695OC. Epub 2004 Oct 22.
Salehian S, Fleming L, Saglani S, Custovic A. Phenotype and endotype based treatment of preschool wheeze. Expert Rev Respir Med. 2023 Jul-Dec;17(10):853-864. doi: 10.1080/17476348.2023.2271832. Epub 2023 Nov 24.
Kwong CG, Bacharier LB. Phenotypes of wheezing and asthma in preschool children. Curr Opin Allergy Clin Immunol. 2019 Apr;19(2):148-153. doi: 10.1097/ACI.0000000000000516.
Other Identifiers
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soh-Med-24-06-20MS
Identifier Type: -
Identifier Source: org_study_id
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