Evaluating Investigational Medical Device for Breast Tumor Diagnosis Using Diffusion Optical Spectroscopy

NCT ID: NCT06597175

Last Updated: 2025-08-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-04-16

Study Completion Date

2024-12-16

Brief Summary

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This is a multicenter, pivotal clinical trial to evaluate the safety and efficacy of a diagnostic device used to assist in the differentiation of breast tumors in patients with breast lesions detected by ultrasound alone or by both ultrasound and mammography.

Detailed Description

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Conditions

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Breast Cancer Breast Tumor Mammary Carcinoma, Human

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Device: ORIGO
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Device: ORIGO

Group Type EXPERIMENTAL

ORIGO

Intervention Type DEVICE

The device measurement is first performed on the breast area with the lesion, followed by the measurement of the corresponding area in the contralateral breast for comparison.

Interventions

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ORIGO

The device measurement is first performed on the breast area with the lesion, followed by the measurement of the corresponding area in the contralateral breast for comparison.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Female aged 19 years or older
* ACR BI-RADS Category 3-5 (5th edition, 2023 update)

Exclusion Criteria

* Pregnant, potentially pregnant, or currently breastfeeding
* Calcifications detected on mammography but do not have corresponding lesions identified on ultrasound
* Biopsy performed on the same breast within 7 days prior to the date of informed consent
* Significant trauma or scarring at the measurement site, or those suffering from mastitis.
* Breast implants, electronic medical devices such as pacemakers, or with a space left in the breast cavity due to implant removal
* History of phototoxic reactions or light sensitivity
Minimum Eligible Age

19 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Olive Healthcare

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Seoul National University Bundang Hospital

Seongnam-si, , South Korea

Site Status

Kangbuk Samsung Hospital

Seoul, , South Korea

Site Status

Korea University Anam Hospital

Seoul, , South Korea

Site Status

Severance Hospital

Seoul, , South Korea

Site Status

Yongin Severance Hospital

Yongin-si, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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ORIGO_E23-01

Identifier Type: -

Identifier Source: org_study_id

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