Membrane Stripping for Cervical Ripening

NCT ID: NCT06591247

Last Updated: 2024-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-07

Study Completion Date

2026-12-31

Brief Summary

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The goal of this interventional study is to evaluate the effectiveness of membrane stripping in cervical ripening compared to double balloon catheter induction.

The study population consists of women undergoing labor induction.

The main questions it aims to answer are:

1. Is membrane stripping as effective as double balloon catheter induction in cervical ripening?
2. What is the influence of membrane stripping on the time required for cervical ripening, delivery duration, and maternal and fetal outcomes compared to balloon induction.

Detailed Description

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Conditions

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Labor, Induced Cervical Ripening Balloon Induction Membrane Stripping Pregnancy Related

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Double Balloon Catheter induction

A Double balloon catheter will be inserted for 12 hours in this group of women

Group Type ACTIVE_COMPARATOR

Double Baloon Catheter

Intervention Type DEVICE

A double Baloon Catheter will be inserted for 12 hours to one of the arms of the study

Membrane stripping

This group of women will undergo membrane stripping twice (every 4-6 hours) over a period of 12 hours

Group Type ACTIVE_COMPARATOR

Membrane Stripping

Intervention Type PROCEDURE

Stripping will be considered as 3-5 rotations of separating the amniotic sac from the cervix and will be perfomed twice (every 4-6 hours)

Interventions

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Double Baloon Catheter

A double Baloon Catheter will be inserted for 12 hours to one of the arms of the study

Intervention Type DEVICE

Membrane Stripping

Stripping will be considered as 3-5 rotations of separating the amniotic sac from the cervix and will be perfomed twice (every 4-6 hours)

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 and above
* Patients with a cervical dilation of at least 1 cm
* Full-term pregnancy
* Cephalic presentation
* No contraindication to vaginal delivery

Exclusion Criteria

* Patients with rupture of membranes
* Patients who do not require cervical ripening and proceed directly to the delivery room for induction with oxytocin
* Patients for whom the use of a double-balloon catheter is contraindicated
* Twin pregnancies
* Pregnancies with macrosomic fetuses where vaginal delivery is contraindicated
* Vaginal deliveries after a cesarean section
* Patients with maternal or fetal pathologies that do not allow for vaginal delivery due to concerns about fetal or maternal distress
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Meir Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Gal Cohen

Gal Cohen MD, Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Meir Medical Center

Kfar Saba, Central District, Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Gal Cohen, MD

Role: CONTACT

+972545915788

Facility Contacts

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Gal Cohen, MD

Role: primary

+972545915788

Renana Izakson, MD

Role: backup

+972506511297

Other Identifiers

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0067-23-MMC

Identifier Type: -

Identifier Source: org_study_id

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