Mobile Chat Messaging for Alcohol Reduction in Patients With Chronic Liver Diseases

NCT ID: NCT06587568

Last Updated: 2025-05-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

106 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-02

Study Completion Date

2025-12-31

Brief Summary

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The goal of this pilot randomized controlled trial is to evaluate the trial feasibility and acceptability of mobile chat messaging for reducing alcohol use among patients with chronic liver diseases. Specific objectives include:

1. To assess whether the eligibility criteria were too restrictive by estimating the eligibility rate
2. To assess how many eligible CLD patients accepted the invitation to participate in the trial
3. To assess the participant retention rate through 6 months after treatment initiation
4. To assess the intervention acceptability in terms of participants' engagement with and rating of the chat messaging intervention.
5. To assess the safety of the intervention
6. To estimate the intervention effect on alcohol use outcomes and liver functions
7. To synthesise data to inform the sample size calculation in the future definitive trial
8. To explore the participants' perception and experiences in the chat-based intervention

Detailed Description

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Conditions

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Chronic Liver Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Mobile chat messaging

Mobile chat messaging + Screening-based alcohol intervention

Group Type EXPERIMENTAL

Mobile chat messaging

Intervention Type BEHAVIORAL

A trained counsellor will interact with a participant individually and provide personalised alcohol reduction information and advice via a mobile instant messaging app in real time for 3 months from randomisation.

Screening, brief intervention and referral to treatment

Intervention Type BEHAVIORAL

Brief counselling (5 to 10 mins) to reduce drinking and a self-help booklet

Brief intervention

Screening-based alcohol intervention only

Group Type ACTIVE_COMPARATOR

Screening, brief intervention and referral to treatment

Intervention Type BEHAVIORAL

Brief counselling (5 to 10 mins) to reduce drinking and a self-help booklet

Interventions

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Mobile chat messaging

A trained counsellor will interact with a participant individually and provide personalised alcohol reduction information and advice via a mobile instant messaging app in real time for 3 months from randomisation.

Intervention Type BEHAVIORAL

Screening, brief intervention and referral to treatment

Brief counselling (5 to 10 mins) to reduce drinking and a self-help booklet

Intervention Type BEHAVIORAL

Other Intervention Names

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SBIRT

Eligibility Criteria

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Inclusion Criteria

1. Age ≥18 years
2. Diagnosed with chronic liver disease
3. Alcohol Use Disorders Identification Test score ≥8
4. Own a smartphone with a mobile instant messaging app installed
5. Able to read and communicate in Chinese

Exclusion Criteria

1. Having a psychiatric or psychological disease or on psychotropic drugs
2. Participating in other alcohol reduction or abstinence programmes
3. Require emergency or in-patient treatment after consultation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Health and Medical Research Fund

OTHER_GOV

Sponsor Role collaborator

The University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Tzu Tsun Luk

Research Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tzu Tsun Luk, PhD, RN

Role: PRINCIPAL_INVESTIGATOR

The University of Hong Kong

Locations

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Queen Mary Hospital

Hong Kong, , Hong Kong

Site Status

Countries

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Hong Kong

Other Identifiers

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21222731

Identifier Type: -

Identifier Source: org_study_id

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