Upper Versus Lower Limb Exercises on Intermittent Claudication in Diabetic Patients

NCT ID: NCT06570564

Last Updated: 2024-08-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-02-20

Study Completion Date

2024-02-20

Brief Summary

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Sixty patients with intermittent claudication and type 2 diabetes mellitus. Their age will ranged from 45-55 years old. They recruited from internal department at Damanhour Medical National Institute (DMNI), Damanhour, Beheira Governorate, Egypt. Patients randomly assigned into three equal groups:

Group (A):

Upper limb exercises group consist of 20 patients. They received arm cranking exercise three times per week for three consecutive months plus routine physiotherapy program.

Group (B):

Lower limb exercises group consist of 20 patients. They received bicycling exercise three times per week for three consecutive months plus routine physiotherapy program.

Group (C):

The control group consisted of 20 patients. They received only routine physiotherapy program.

Detailed Description

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1. Subjects:

Sixty patients with intermittent claudication and type 2 diabetes mellitus. Their age ranged from 45-55 years old. They recruited from internal department at Damanhour Medical National Institute (DMNI), Damanhour, Beheira Governorate, Egypt. Patients randomly assigned into three equal groups:

Group (A):

Upper limb exercises group consist of 20 patients. They received arm cranking exercise three times per week for three consecutive months plus routine physiotherapy program.

Group (B):

Lower limb exercises group consist of 20 patients. They received bicycling exercise three times per week for three consecutive months plus routine physiotherapy program.

Group (C):

The control group consisted of 20 patients. They received only routine physiotherapy program.
2. Equipment:

Measurement equipment:

1. The Treadmill:

All patients were tested Maximum walking distance and Pain free walking distance by walking in the treadmill.
2. Ankle/brachial indices (ABI) Doppler Ultrasound Machine
3. All patients were tested HbA1C before and after the treatment in medical analysis lab department at Damanhour Medical National Institute (DMNI).

Therapeutic equipment:

1. The arm crank ergometer
2. bicycle ergometer

Conditions

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Intermittent Claudication

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Upper limb exercises group.

Upper limb exercises group consist of 20 patients. They received arm cranking exercise and routine physiotherapy program.

Group Type EXPERIMENTAL

The arm crank ergometer

Intervention Type DEVICE

Before starting the program, patients will perform an adaptation session for familiarization with the ergometer and also to identify the training load. For this, patients will perform 10 bouts of two minutes of exercising with a minimum load and two minute passive intervals between bouts. Patients will be instructed to maintain 50 revolutions per minute (RPM) during the exercise. Subsequently, to determine the training load for each session, patients will perform a progressive test where the load will be increased by 10 watts every minute of the test, following the protocol of two minutes of exercise with two minutes of interval

treadmill

Intervention Type DEVICE

Supervised treadmill exercise as routine physiotherapy program

Lower limb exercises group.

Lower limb exercises group consist of 20 patients. They received bicycling exercise and routine physiotherapy program.

Group Type EXPERIMENTAL

bicycle ergometer

Intervention Type DEVICE

bicycle ergometer program will consist of a bicycling exercise 3 days per week. Exercise intensity was set at 70% of maximal load with 30 minutes per session. The exercise protocol also incorporated warm-up and cool-down sessions that involved stretches of the major lower limb muscle groups (total exercise time, 40-60 minutes)

treadmill

Intervention Type DEVICE

Supervised treadmill exercise as routine physiotherapy program

The control group.

The control group consisted of 20 patients. They received only routine physiotherapy program.

Group Type EXPERIMENTAL

treadmill

Intervention Type DEVICE

Supervised treadmill exercise as routine physiotherapy program

Interventions

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The arm crank ergometer

Before starting the program, patients will perform an adaptation session for familiarization with the ergometer and also to identify the training load. For this, patients will perform 10 bouts of two minutes of exercising with a minimum load and two minute passive intervals between bouts. Patients will be instructed to maintain 50 revolutions per minute (RPM) during the exercise. Subsequently, to determine the training load for each session, patients will perform a progressive test where the load will be increased by 10 watts every minute of the test, following the protocol of two minutes of exercise with two minutes of interval

Intervention Type DEVICE

bicycle ergometer

bicycle ergometer program will consist of a bicycling exercise 3 days per week. Exercise intensity was set at 70% of maximal load with 30 minutes per session. The exercise protocol also incorporated warm-up and cool-down sessions that involved stretches of the major lower limb muscle groups (total exercise time, 40-60 minutes)

Intervention Type DEVICE

treadmill

Supervised treadmill exercise as routine physiotherapy program

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Sixty patients with type 2 diabetes mellitus and intermittent claudication.
* Patients with diabetes at least 5 years.
* Both genders were included.
* Their age will be ranged from 45-55 years old.
* Patients referred from physician of internal medicine diagnosed as controlled type 2 diabetes (HbA1c 7-7.5%) for the previous 3 months.
* Their body mass index will be ranged from 25.0 to 34.9 kg/m2.

Exclusion Criteria

* Pregnant women.
* Malignancy.
* Other medical conditions such as uncontrolled hypertension and osteoporosis.
* Past medical history included conditions that may influence the provision of physiotherapy interventions such as (severe asthma, chronic airflow limitation, bronchiectasis, ankylosing spondylitis or lumbar disc prolapse).
Minimum Eligible Age

45 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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El-Sayed Essam

principle investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Damanhour teaching hospital

Damanhūr, Damanhour, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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16122022

Identifier Type: -

Identifier Source: org_study_id

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