Effect of Core Stability Versus Conventional Exercise for Functional Ambulation of Calf Muscle

NCT ID: NCT06766877

Last Updated: 2025-01-10

Basic Information

• Recruitment Status: ENROLLING_BY_INVITATION
• Clinical Phase: NA
• Total Enrollment: 100 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-07-22
• Study Completion Date: 2025-02-23

Brief Summary

Knee osteoarthritis (KOA) is a degenerative joint disease causing pain, stiffness, and reduced quality of life. While treatments often focus on drugs or surgery, noninvasive exercises like core stabilization and ankle/foot strengthening show potential but lack comparative studies. Understanding anatomical factors like Achilles tendon (AT) thickness is crucial for targeted rehabilitation, though measurement reliability remains an issue. This study aims to compare the effects of these exercises on KOA symptoms and evaluate the use of digital calipers for AT thickness measurement, aiming to enhance clinical management of KOA.

Detailed Description

The objective of the study is:

1. To determine the interrater and intrarater reliability of digital calliper to measure the side to side Achilles tendon thickness.

2. To determine the impact of 24 sessions of core stability translated in gait ambulation.

3. determines the relationships between Achilles tendon thickness (ATT), knee symptoms/functions, and foot alignment in knee OA patients, considering their interconnected biomechanical nature.

4. compare the effects of core stability and ankle-foot strengthening exercises on clinical outcomes in KOA patients

Conditions

Knee Osteoarthritis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: TRIPLE

Study Groups

Core Stability

Core Stability exercises:

Bridging Lateral Step up etc

Group Type: EXPERIMENTAL

core stability exercise

Intervention Type: OTHER

1. Isometric quadriceps exercises involving knee extension

2. Maximum isometric exercise for the quadriceps

Foot-ankle strengthening exercise

resistance exercises with proper warm up and cool down

Group Type: ACTIVE_COMPARATOR

foot-ankle strengthening exercise

Intervention Type: OTHER

1. Isometric quadriceps exercises involving knee extension

2. Maximum isometric exercise for the quadriceps

Interventions

core stability exercise

1. Isometric quadriceps exercises involving knee extension

2. Maximum isometric exercise for the quadriceps

Intervention Type: OTHER

foot-ankle strengthening exercise

1. Isometric quadriceps exercises involving knee extension

2. Maximum isometric exercise for the quadriceps

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• 40 years old, had been diagnosed with KOA based on ACR, and

• having Grade II or III osteoarthritis by K/L criteria.

Exclusion Criteria

• post-traumatic osteoarthritis
• lower limb sensorimotor dysfunction,
• Any history of knee fracture/ tumor/ infection and hip/knee surgery.
• Total Knee Replacement patients.
• Neurological disease.
• Patient received physical therapy treatment from last 6 months.
• Inflammatory Arthritis (Rheumatoid Arthritis)
• Use of any intra-articular injections (steroid/ hyaluronic acid/ PRP.) from last 3-6 months.

• Minimum Eligible Age: 40 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Dow University of Health Sciences

OTHER

Sponsor Role: lead

Responsible Party

Shaikh Nabi Bukhsh Nazir

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

SHAIKH NABI BUKHSH NAZIR, PhD Scholar

Role: PRINCIPAL_INVESTIGATOR

Dow University of Health Sciences/ Baqai Medical University

Locations

BIPTRM

Karachi, Sindh, Pakistan

Countries

Pakistan

Other Identifiers

BMU/Approval?

Identifier Type: -

Identifier Source: org_study_id