Cardiovascular and Metabolic Sciences Biorepository

NCT ID: NCT06560424

Last Updated: 2025-10-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-18

Study Completion Date

2050-12-31

Brief Summary

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The purpose of the Cardiovascular and Metabolic Sciences Biorepository is to collect and store information and biospecimens (blood, urine, stool, and heart tissue) from patients with and without cardiovascular and metabolic diseases to create a readily available biorepository of samples and related medical health information to expedite future research into the causes and consequences of cardiovascular and metabolic diseases.

Detailed Description

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Heart disease is the leading cause of death in the United States and other vascular diseases, like stroke, and metabolic diseases, like diabetes, are consistently in the top ten causes of death (CDC, 2024). There is clearly a need for continuing research and innovation into improved diagnosis and treatment of these diseases.

The goal of this biorepository is to provide an easily accessible collection of samples for researchers to utilize. The biorepository will also serve as a place to store residual samples from other cardiovascular disease (CVD) studies for future use, to make the best use of these biospecimen resources.

Conditions

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Cardiovascular Diseases Metabolic Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Personal History of Cardiovascular or Metabolic Diseases

Persons who have a diagnosis of a cardiovascular or metabolic disease. Examples of cardiovascular diseases are: heart failure, arrhythmias, high cholesterol, coronary artery disease, heart attack, and stroke. Examples of metabolic diseases are: diabetes, metabolic syndrome, and hemochromatosis.

No interventions assigned to this group

Family History of Cardiovascular or Metabolic Diseases

Persons without a personal diagnosis of any cardiovascular or metabolic disease but with a family history in a first-degree relative of one of those diseases.

No interventions assigned to this group

Healthy Controls

No personal or family (first-degree relative) history of cardiovascular or metabolic diseases.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Willing and able to sign the informed consent document

Exclusion Criteria

* Chronic anemia (hemoglobin consistently \<9 g/L)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Cleveland Clinic

OTHER

Sponsor Role lead

Responsible Party

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Wilson Tang

Staff Physician, Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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W. H. Wilson Tang, MD

Role: PRINCIPAL_INVESTIGATOR

The Cleveland Clinic

Locations

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Cleveland Clinic Main Campus

Cleveland, Ohio, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Jennifer Wilcox, BA

Role: CONTACT

216-636-6153

Tim Engelman, LPN

Role: CONTACT

216-636-6153

Facility Contacts

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Jennifer Wilcox, BA

Role: primary

216-636-6153

Timothy Engelman, LPN

Role: backup

216-636-6153

Other Identifiers

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24-708

Identifier Type: -

Identifier Source: org_study_id

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