Study of ONO-4578 and XELOX/FOLFOX Plus Bevacizumab in Colorectal Cancer
NCT ID: NCT06547385
Last Updated: 2024-08-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
PHASE1
40 participants
INTERVENTIONAL
2021-01-13
2027-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SEQUENTIAL
TREATMENT
NONE
Study Groups
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ONO-4578+ONO-4538+XELOX plus bevacizumab
ONO-4578
Specified dose on specified days
ONO-4538
Specified dose on specified days
Capecitabine
Specified dose on specified days
Oxaliplatin
Specified dose on specified days
Bevacizumab
Specified dose on specified days
ONO-4578+ONO-4538+FOLFOX plus bevacizumab
ONO-4578
Specified dose on specified days
ONO-4538
Specified dose on specified days
Oxaliplatin
Specified dose on specified days
Fluorouracil
Specified dose on specified days
Calcium Levofolinate Hydrateb
Specified dose on specified days
Bevacizumab
Specified dose on specified days
Interventions
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ONO-4578
Specified dose on specified days
ONO-4538
Specified dose on specified days
Capecitabine
Specified dose on specified days
Oxaliplatin
Specified dose on specified days
Fluorouracil
Specified dose on specified days
Calcium Levofolinate Hydrateb
Specified dose on specified days
Bevacizumab
Specified dose on specified days
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Life expectancy of at least 3 months
* Patients with ECOG performance status 0 or 1
Exclusion Criteria
* Patients are unable to swallow oral medications
20 Years
ALL
No
Sponsors
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Ono Pharmaceutical Co. Ltd
INDUSTRY
Responsible Party
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Principal Investigators
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Project Leader
Role: STUDY_DIRECTOR
Ono Pharmaceutical Co. Ltd
Locations
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National Cancer Center Hospital East
Kashiwa-shi, Chiba, Japan
Kobe City Hospital Organization Kobe City Medical Center General Hospital
Kobe, Hyōgo, Japan
Kanagawa Cancer Center
Yokohama, Kanagawa, Japan
Saitama Cancer Center
Ina, Kitaadati-gun, Saitama, Japan
NHO Osaka National Hospital
Osaka, Osaka, Japan
Osaka General Medical Center
Osaka, Osaka, Japan
Osaka Medical and Pharmaceutical University Hospital
Takatsuki-shi, Osaka, Japan
Saitama Medical University International Medical Center
Hidaka-shi, Saitama, Japan
Cancer Institute Hospital of JFCR
Koto-Ku, Tokyo, Japan
Countries
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Other Identifiers
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ONO-4578-02
Identifier Type: -
Identifier Source: org_study_id
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