Our Whole Lives Gemini: Virtual Integrative Medical Group Visits for Managing Chronic Pain

NCT ID: NCT06515925

Last Updated: 2025-03-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

212 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-01

Study Completion Date

2025-11-30

Brief Summary

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The goal of this research study is to test the efficacy of a non-prescription medicine, web-based platform solution for patients with chronic pain, to improve pain self-management and related outcomes. The main question investigators aim to answer is; would the use of this web-based intervention plus an online group visit compared to control result in better pain-related outcomes and improved pain impact?

Detailed Description

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This study has 6 mandatory components and 1 optional component:

* Recruitment Screening Call
* Informed Consent Session
* Baseline Survey Session
* Intervention: Engagement with the Our Whole Lives (OWL) an e-health platform: For 9 weeks, participants will all have access to a mindfulness program within OWL, optimized for people with chronic pain.
* Live-Online Mindfulness Group weekly
* Control: Low dose engagement with OWL with no group engagement.
* Follow-Up Survey Sessions at Week 10, Week 16, and Week 24.
* Online Focus Group/Individual Interview. Participants will be asked to participate in an OPTIONAL individual interview, or a one-hour focus group with other participants in the study who used the OWL website as well.

Researchers will compare two groups that will be using the web-based platform. Each group will have different engagement content from the web-based platform and investigators will see if it affects overall chronic pain and pain management.

Conditions

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Chronic Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Our Whole Lives (OWL)

Our Whole Lives (OWL) is a 9-week online curriculum on the GEMINI platform. OWL is a nine-session, web-accessible, self-paced mindfulness curriculum that has interactive components of self-monitoring and social support (online community).

Group Type EXPERIMENTAL

Our Whole Lives (OWL)

Intervention Type BEHAVIORAL

OWL is a nine-session, web-accessible, self-paced mindfulness curriculum that has interactive components of self-monitoring and social support (online community). Our Whole Lives (OWL) online curriculum of self-management topics such as mindfulness, mind-body practices, education about chronic pain therapies, stress reduction, sleep, and nutrition.

Once a week for 9 weeks participants will attend a 1.5 -2-hour online group session via Zoom or Google Meets, accessing it through GEMINI platform.

Low Dose Mindfulness Training

The GEMINI platform will facilitate the delivery of a low-dose mindfulness version of Our Whole Lives program. Participants will interface with the GEMINI platform's static content.

Group Type ACTIVE_COMPARATOR

Low Dose Mindfulness Training

Intervention Type BEHAVIORAL

The GEMINI platform will facilitate the delivery of a low-dose version of Our Whole Lives program. OWL in this arm is a nine-session, web-accessible, self-paced curriculum, self-monitoring. Participants will interface with the GEMINI platform's static content.

Interventions

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Our Whole Lives (OWL)

OWL is a nine-session, web-accessible, self-paced mindfulness curriculum that has interactive components of self-monitoring and social support (online community). Our Whole Lives (OWL) online curriculum of self-management topics such as mindfulness, mind-body practices, education about chronic pain therapies, stress reduction, sleep, and nutrition.

Once a week for 9 weeks participants will attend a 1.5 -2-hour online group session via Zoom or Google Meets, accessing it through GEMINI platform.

Intervention Type BEHAVIORAL

Low Dose Mindfulness Training

The GEMINI platform will facilitate the delivery of a low-dose version of Our Whole Lives program. OWL in this arm is a nine-session, web-accessible, self-paced curriculum, self-monitoring. Participants will interface with the GEMINI platform's static content.

Intervention Type BEHAVIORAL

Other Intervention Names

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Low dose comparator

Eligibility Criteria

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Inclusion Criteria

* English-speaking adults
* Over the age of 18
* Experiencing chronic musculoskeletal pain. (Pain may have more than one source; Pain must be non-malignant; Participant must have an average pain intensity of ≥ 4 (1 out of 10) in the past 7 days; Participant must meet the chronic criteria of a pain problem that has persisted at least 3 months, and has resulted in pain on at least half the days in the past 6 months)

Exclusion Criteria

* Inability to understand English at a level necessary for informed consent and understanding participation instructions, and participating in the group;
* Serious underlying systemic or co-morbid conditions or life event that precludes physical or cognitive ability to participate in the study.
* Severe depression
* Current mania or psychosis;
* Active heroin or cocaine use in the past 3 months
* Heavy alcohol use
* Known or planned pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Center for Complementary and Integrative Health (NCCIH)

NIH

Sponsor Role collaborator

BrightOutcome

INDUSTRY

Sponsor Role collaborator

Cambridge Health Alliance

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Zev Schuman-Olivier, MD

Role: STUDY_DIRECTOR

Cambridge Health Alliance

Paula Gardiner, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

Cambridge Health Alliance

Niina Haas, PHD

Role: PRINCIPAL_INVESTIGATOR

BrightOutcome

Locations

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Cambridge Health Alliance Center for Mindfulness and Compassion

Malden, Massachusetts, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Paula Gardiner

Role: CONTACT

617 806 8735

Alexandra Comeau

Role: CONTACT

617-806-8735

Facility Contacts

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Paula Gardiner

Role: primary

Alexandra Comeau

Role: backup

617-806-8735

References

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Deyo RA, Dworkin SF, Amtmann D, Andersson G, Borenstein D, Carragee E, Carrino J, Chou R, Cook K, DeLitto A, Goertz C, Khalsa P, Loeser J, Mackey S, Panagis J, Rainville J, Tosteson T, Turk D, Von Korff M, Weiner DK. Report of the NIH Task Force on research standards for chronic low back pain. J Pain. 2014 Jun;15(6):569-85. doi: 10.1016/j.jpain.2014.03.005. Epub 2014 Apr 29.

Reference Type BACKGROUND
PMID: 24787228 (View on PubMed)

Deyo RA, Katrina Ramsey, Buckley DI, Michaels L, Kobus A, Eckstrom E, Forro V, Morris C. Performance of a Patient Reported Outcomes Measurement Information System (PROMIS) Short Form in Older Adults with Chronic Musculoskeletal Pain. Pain Med. 2016 Feb;17(2):314-24. doi: 10.1093/pm/pnv046.

Reference Type BACKGROUND
PMID: 26814279 (View on PubMed)

Nicholas MK. The pain self-efficacy questionnaire: Taking pain into account. Eur J Pain. 2007 Feb;11(2):153-63. doi: 10.1016/j.ejpain.2005.12.008. Epub 2006 Jan 30.

Reference Type BACKGROUND
PMID: 16446108 (View on PubMed)

Sobell LC, Sobell MB. Timeline follow-back. Measuring alcohol consumption. Springer;1992:41-72.

Reference Type BACKGROUND

Fals-Stewart W, O'Farrell TJ, Freitas TT, McFarlin SK, Rutigliano P. The timeline followback reports of psychoactive substance use by drug-abusing patients: psychometric properties. J Consult Clin Psychol. 2000 Feb;68(1):134-44. doi: 10.1037//0022-006x.68.1.134.

Reference Type BACKGROUND
PMID: 10710848 (View on PubMed)

Provided Documents

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Document Type: Informed Consent Form

View Document

Other Identifiers

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1R44AT012302-01A1

Identifier Type: NIH

Identifier Source: secondary_id

View Link

CHA-IRB-23-24-260

Identifier Type: -

Identifier Source: org_study_id

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