Biomarkers in Parkinsonian Syndromes

NCT ID: NCT06501469

Last Updated: 2024-07-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-23

Study Completion Date

2030-03-25

Brief Summary

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This is a prospective observational study to identify biomarkers in parkinson syndromes. Patients with parkinsonian syndromes at the early stages of disease will be recruited and will be followed up until their established clinical diagnosis or for at least 5 years. In this population, imaging and wet biomarkers as well as clinical data will b systematically collected.

Detailed Description

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Conditions

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Parkinson Disease Progressive Supranuclear Palsy Multiple System Atrophy Atypical Parkinsonism Parkinsonism

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Exclusion Criteria

* Drug-induced parkinsonism (eg, neuroleptics, lithium, valproic acid, metoclopramide).
* Metabolic conditions related parkinsonism (eg, Wilson's disease, hypoparathyroidism).
* Structural lesions on brain magnetic resonance imaging (MRI) that explain the symptoms, such as normal pressure hydrocephalus, moderate to severe chronic vascular encephalopathy, cerebral infarction, neoplasm
* Other serious diseases that indicate a life expectancy of \<5 years.
* Active participation in other interventional clinical studies
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Biomedical Research Foundation, Academy of Athens

OTHER

Sponsor Role collaborator

Non-profit organization for scientific research in Parkinson's disease and related disorders

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Maria Stamelou, Prof Dr

Role: PRINCIPAL_INVESTIGATOR

HYGEIA Hospital

Locations

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HYGEIA Hospital, Parkinson's disease and Movement Disorders Department

Athens, , Greece

Site Status RECRUITING

Countries

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Greece

Central Contacts

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Maria Stamelou, Prof Dr

Role: CONTACT

+302106867303

Facility Contacts

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Maria Stamelou, Prof Dr

Role: primary

+302106867000 ext. 337

Other Identifiers

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642

Identifier Type: -

Identifier Source: org_study_id

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