Real-world Clinical Outcomes of Patients With Early-stage Lung Cancer After the Surgery

NCT ID: NCT06483698

Last Updated: 2025-08-29

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 20000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-03-01
• Study Completion Date: 2034-12-31

Brief Summary

The goal of this observational study is to evaluate the efficacy and long-term clinical outcomes of early-stage lung cancer patients who have received surgery using the real-world data. The main questions it aims to answer are:

• What is the best surgical strategy for patients with early-stage lung cancer?
• What are the risk factors for early-stage lung cancer? Participants will receive surgery and the study will analyze the real-world data.

Detailed Description

This observational study aims to comprehensively evaluate the effectiveness and long-term clinical outcomes of surgical interventions in early-stage lung cancer patients, utilizing real-world data.

Central to this investigation are two key questions:

• What is the optimal surgical approach for managing early-stage lung cancer?
• What are the primary risk factors associated with the development of early-stage lung cancer? Participants will undergo surgical procedures, and through rigorous analysis of real-world data, this study endeavors to provide nuanced insights into these fundamental queries, fostering advancements in clinical decision-making and patient management strategies.

Conditions

Lung Cancer

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

Sublobar resection group

Patients in this group have received Sublobar resection.

Sublobar resection

Intervention Type: OTHER

Sublobar resection is a series of surgical approaches for lung cancer.

Lobectomy group

Patients in this group have received lobectomy.

Lobectomy

Intervention Type: OTHER

Lobectomy is the surgical approach for lung cancer.

Interventions

Sublobar resection

Sublobar resection is a series of surgical approaches for lung cancer.

Intervention Type: OTHER

Lobectomy

Lobectomy is the surgical approach for lung cancer.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

1. Aged between 18 and 85;

2. Did not receive neoadjuvant therapy before surgery;

3. No history of radiation therapy;

4. Eastern Cooperative Oncology Group (ECOG) score is 0-1;

5. Have complete clinically relevant information including imaging data;

6. All patients underwent relevant preoperative examinations;

7. Stage I lung cancer (International Association for the Study of Lung Cancer/The Union for International Cancer Control staging eighth edition);

Exclusion Criteria

1. Have previously received chemotherapy, radiotherapy and other anti-tumor therapy;

2. Data loss and error in medical records due to human/objective reasons.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 85 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Shugeng Gao, MD

Role: PRINCIPAL_INVESTIGATOR

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Locations

Shugeng Gao

Beijing, Beijing Municipality, China

Site Status: RECRUITING

Countries

China

Central Contacts

Shugeng Gao, MD

Role: CONTACT

gaoshugeng@cicams.ac.cn

8610-87788177

Facility Contacts

Shugeng Gao, MD

Role: primary

gaoshugeng@cicams.ac.cn

010-87788177

Other Identifiers

23/516-4259

Identifier Type: -

Identifier Source: org_study_id