Research on Nutritional Risk Indexes and Inflammatory Indicators in Postoperative Complications and Prognosis of Epithelial Ovarian Cancer Patients

NCT ID: NCT06483399

Last Updated: 2024-07-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1108 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-01-01

Study Completion Date

2023-02-28

Brief Summary

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The goal of this observational study is to explore the influence and predictive significance of nutritional risk indicators and inflammatory indicators on postoperative complications and prognosis of patients with epithelial ovarian cancer (EOC). The main question it aims to answer is:

Can preoperative nutritional risk and inflammatory indexes predict postoperative complications? Do preoperative nutritional risk and inflammatory indexes better predict the prognosis of patients with epithelial ovarian cancer? Which index is the best predictor of postoperative complications or prognosis for patients?

Detailed Description

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Conditions

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Epithelial Ovarian Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Low [index] group

The patients were grouped according to the cut-off value of each index, and the patients whose index value was lower than the cut-off value were classified as the Low \[index\] group.

No interventions assigned to this group

High [index] group

The patients were grouped according to the cut-off value of each index, and the patients whose index value was higher than the cut-off value were classified as the High \[index\] group.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. histologically confirmed primary epithelial ovarian, peritoneal, and fallopian tube cancers.
2. patients received comprehensive staged surgery or debulking surgery.
3. available data of laboratory examination within 7 days before the surgery.

Exclusion Criteria

1. borderline ovarian tumor.
2. receipt of neoadjuvant chemotherapy.
3. presence of other conditions influencing laboratory data, like hepatitis, kidney disease, autoimmune diseases, infectious diseases, blood disease, etc.
4. concurrent cancer in other organs.
5. absence of surgery or biopsy only.
6. multiple staged surgeries.
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Qinglei Gao

OTHER

Sponsor Role lead

Responsible Party

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Qinglei Gao

Professor

Responsibility Role SPONSOR_INVESTIGATOR

References

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Liu X, Li M, Zhao Y, Jiao X, Yu Y, Li R, Zeng S, Chi J, Ma G, Huo Y, Peng Z, Liu J, Zhou Q, Zou D, Wang L, Li Q, Wang J, Yao S, Chen Y, Ma D, Hu T, Gao Q. The impact of preoperative immunonutritional status on postoperative complications in ovarian cancer. J Ovarian Res. 2025 Apr 29;18(1):88. doi: 10.1186/s13048-025-01624-3.

Reference Type DERIVED
PMID: 40301987 (View on PubMed)

Other Identifiers

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2024-TJ-NIOC

Identifier Type: -

Identifier Source: org_study_id

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