Breathing Exercises on Lung Function

NCT ID: NCT06472167

Last Updated: 2025-05-29

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-06-01
• Study Completion Date: 2025-12-10

Brief Summary

aim of this study is to evaluate the efficacy of pulmonary rehabilitation program as a non-pharmacological treatment method to: Improve functional capacity as assessed by six-minute walking distance (6MWD) test. Improve dyspnea level as assessed by Medical Research Council (MRC) dyspnea scale. Improve pulmonary function tests and arterial blood gas.

Detailed Description

Breathing exercises offer numerous benefits for individuals with chronic airway diseases, such as chronic obstructive pulmonary disease (COPD), asthma and bronchiectasis. These exercises help improve respiratory function, reduce symptoms, and enhance the overall quality of life.Techniques such as diaphragmatic breathing, incentive spirometer and pursed lip breathing help patients use their lungs more effectively. Breathing exercises can enhance lung function by increasing the efficiency of the respiratory muscles and improving ventilation. Asthma is a chronic inflammatory disorder of the airways classified as intermittent or persistent (mild, moderate or severe), according to the presence of diurnal and nocturnal symptoms, necessity of medication, frequency of exacerbation, physical activity limitations and pulmonary function. All of these symptoms deteriorate in the patient's quality of life and psychological well-being and restrict daily living physical activities (DLPA). Asthma symptoms experienced during daily living physical activities (DLPA) or the fear of triggering symptoms may keep asthmatic subjects from engaging in physical exercise, and the patients tend to be less physically active and less conditioned than healthy individuals. In addition, asthmatic patients have higher levels of anxiety and depression that have been shown to be associated with an increased number of exacerbations and the diagnosis of severe asthma. These psychosocial disorders can modify the respiratory breathing pattern, which leads to irregular breathing, frequent sighing, and predominant thoracic breathing. These irregular breathing patterns increase the number of respiratory (breathlessness, chest tightness and pain) and non-respiratory symptoms (anxiety, dizziness and fatigue). Recent Global Initiative for Chronic Obstructive Pulmonary Disease guidelines (GOLD) underline the importance of pulmonary rehabilitation (PR) as a part of an integrative multidisciplinary approach regardless of the stage of disease

Conditions

Breathing Exercises

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Chronic airway diseases treated by medication

Chronic airway diseases treated by medication without breathing exercises

Group Type: NO_INTERVENTION

No interventions assigned to this group

Chronic airway diseases treated by medication with breathing exercises

Chronic airway diseases treated by medication and breathing exercises

Group Type: ACTIVE_COMPARATOR

Breathing exercises

Intervention Type: BEHAVIORAL

Breathing exercises as diaphragmatic breathing exercises and pursued lip breathing and incentive spirometry

Interventions

Breathing exercises

Breathing exercises as diaphragmatic breathing exercises and pursued lip breathing and incentive spirometry

Intervention Type: BEHAVIORAL

Other Intervention Names

Diaphragmatic Breathing exercise; Pursued lip breathing

Eligibility Criteria

Inclusion Criteria

• The patients fulfilled the criteria for COPD: the presence of a post bronchodilator FEV1 < 80% predicated together with an FEV1/FVC <0.70confirm the presence of airflow limitation that is not fully reversible.
• COPD patients ranging from mild to severe according to GOLD [stages I-IV].
• Asthmatic patients receive medical treatment for at least 6 months; and clinically stable (i.e., no exacerbation or changes in medication for ≥30 days).
• None of the individuals had been engaged in any exercise-training program before participating in the study.
• Optimized medical therapy according to GOLD & Global Initiative for Asthma (GINA)
• Clinically stable COPD and asthmatic patients (not suffering from a recent respiratory tract infection).
• All patients are Ex-smoker

Exclusion Criteria

• Age <18 years.
• Pregnancy
• Current Smokers
• Patients that are incapable of exercising; unable to understand any questionnaire
• Multiple co- morbidity (e.g., cardiovascular diseases, active cancer)
• Neuromuscular disease as Myasthenia gravis, kypho-scoliosis
• Diaphragmatic Paralysis (paralyzed diaphragm exhibiting abnormal paradoxical movement, i.e., moving in a cranial direction during inspiration).

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Mansoura University Hospital

OTHER

Sponsor Role: lead

Responsible Party

Mohamed Abd Elmoniem Mohamed

Lecturer of chest medicine

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Mohamed AbdElmoniem

Role: PRINCIPAL_INVESTIGATOR

Lecturer of chest medicine faculty of medicine Mansoura university

Locations

Mohamed AbdElmoniem

Al Mansurah, , Egypt

Site Status: RECRUITING

Countries

Egypt

Central Contacts

Mohamed AbdElmoniem

Role: CONTACT

dr.m1993@mans.edu.eg

01014008473

Mohamed Ahmed Ibrahim

Role: CONTACT

Facility Contacts

Mohamed AbdElmoniem

Role: primary

dr.m1993@mans.edu.eg

01014008473

Mohamed Ahmed Ibrahim

Role: backup

dr.m1993@mans.edu.eg

01014008473

Other Identifiers

R.24.05.2638

Identifier Type: -

Identifier Source: org_study_id