Relationship Between Serum N/OFQ and Acute Myeloid Cell Leukemia

NCT ID: NCT06469047

Last Updated: 2024-06-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-06-20

Study Completion Date

2024-12-31

Brief Summary

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Patients diagnosed with acute myeloid leukemia in the Second Hospital of Shanxi Medical University were selected and divided into the newly diagnosed group, the relapsed group, the complete remission group as the experimental group, and the healthy physical examination subjects as the control group. The relationship between IL-1β, catecholamine and norkephalin in peripheral blood of the experimental group and the control group was observed. According to the literature, the experimental group was significantly higher than the control group. In the experimental group, the newly diagnosed group was higher than the relapse group, and the relapse group was higher than the complete remission group, and the correlation was positive, and the difference was statistically significant.

Detailed Description

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Conditions

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AML

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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the newly diagnosed group

Enzyme-linked immunosorbent assay

Intervention Type DIAGNOSTIC_TEST

Serum N/OFQ , IL-1β and NE levels were detected.

the relapsed group

Enzyme-linked immunosorbent assay

Intervention Type DIAGNOSTIC_TEST

Serum N/OFQ , IL-1β and NE levels were detected.

the complete remission group

Enzyme-linked immunosorbent assay

Intervention Type DIAGNOSTIC_TEST

Serum N/OFQ , IL-1β and NE levels were detected.

the control group

Enzyme-linked immunosorbent assay

Intervention Type DIAGNOSTIC_TEST

Serum N/OFQ , IL-1β and NE levels were detected.

Interventions

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Enzyme-linked immunosorbent assay

Serum N/OFQ , IL-1β and NE levels were detected.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* In accordance with adult acute myeloid leukemia (non-acute promyelocytic leukemia)The diagnostic criteria for AML in the Chinese Diagnosis and Treatment Guidelines (2017 edition); ②Leukocyte count ≤ 25×109/L;

* No treatment has been received in the past 6 months.

* None of the candidates are related and known this study, and sign the informed consent.

Exclusion Criteria

* Patients who are allergic to the drugs used in this study;

* People with mental illness or cognitive impairment;

* Patients with infectious diseases; ④Patients with severe heart, liver, kidney and other organ function lesions; ⑤ Combined with other malignant swelling. The tumor.
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Second Hospital of Shanxi Medical University

OTHER

Sponsor Role lead

Responsible Party

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Zheng Guo

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Second Hospital of Shanxi Medical University

Taiyuan, Shanxi, China

Site Status

Countries

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China

Other Identifiers

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Hanyi20240408

Identifier Type: -

Identifier Source: org_study_id

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